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2009

Kondo, J

[Exploring the "motion" = "function" of the ribosomal A-site molecular switch] Article de journal

Tanpakushitsu Kakusan Koso, 54 (11), p. 1356-62, 2009, (0039-9450 (Print) 0039-9450 (Linking) Journal Article Review).

BibTeX | Étiquettes: *Binding, *RNA/genetics, Agents/adverse, Anti-Bacterial, Bacteria/drug, Biosynthesis/genetics, Crystallography, Disorders/genetics, effects, effects/pharmacology, Hearing, Humans, Mutation, Protein, Ribosomes/chemistry/*genetics/*physiology, RNA, Sites, Transfer, Untranslated, WESTHOF, X-Ray

Messmer, M; Putz, J; Suzuki, T; Sauter, C; Sissler, M; Florentz, C

Tertiary network in mammalian mitochondrial tRNAAsp revealed by solution probing and phylogeny Article de journal

Nucleic Acids Res, 37 (20), p. 6881-6895, 2009, ISBN: 19767615, (1362-4962 (Electronic) 0305-1048 (Linking) Journal Article Research Support, Non-U.S. Gov't).

Résumé | Liens | BibTeX | Étiquettes: Asp/*chemistry/*metabolism Transcription, FLORENTZ, FLORENTZ Base Sequence Databases, Genetic, Nucleic Acid Humans Molecular Sequence Data Nucleic Acid Conformation Phylogeny RNA/*chemistry/*metabolism RNA, SISSLER, Transfer, Unité ARN

Messmer, M; Gaudry, A; Sissler, M; Florentz, C

Pathology-related mutation A7526G (A9G) helps in the understanding of the 3D structural core of human mitochondrial tRNA(Asp) Article de journal

RNA, 15 (8), p. 1462-1468, 2009, ISBN: 19535463, (1469-9001 (Electronic) Letter Research Support, Non-U.S. Gov't).

Résumé | Liens | BibTeX | Étiquettes: Asp/*chemistry/*genetics/metabolism Transfer RNA Aminoacylation/genetics, FLORENTZ, FLORENTZ Binding Sites/genetics Humans Kinetics Mitochondrial Myopathies/genetics/metabolism/pathology Models, Missense Nucleic Acid Conformation RNA/*chemistry/*genetics/metabolism RNA, Molecular Mutation, SISSLER, Transfer, Unité ARN

Giannouli, S; Kyritsis, A; Malissovas, N; Becker, H D; Stathopoulos, C

On the role of an unusual tRNAGly isoacceptor in Staphylococcus aureus Article de journal

Biochimie, 91 (3), p. 344-351, 2009, ISBN: 19014993, (1638-6183 (Electronic) Journal Article Research Support, Non-U.S. Gov't).

Résumé | Liens | BibTeX | Étiquettes: Bacterial Glycine-tRNA Ligase/genetics/*metabolism Peptide Elongation Factor Tu/metabolism RNA, Gly/*genetics/*metabolism Recombinant Proteins/metabolism Sequence Analysis, KERN Anticodon/metabolism Computational Biology/methods Genes, RNA Staphylococcus aureus/*genetics/*metabolism Transfer RNA Aminoacylation/genetics, Transfer, Unité ARN

Frechin, M; Senger, B; Brayé, M; Kern, D; Martin, R P; Becker, H D

Yeast mitochondrial Gln-tRNA(Gln) is generated by a GatFAB-mediated transamidation pathway involving Arc1p-controlled subcellular sorting of cytosolic GluRS Article de journal

Genes Dev, 23 (9), p. 1119-1130, 2009, ISBN: 19417106, (1549-5477 (Electronic) Journal Article Research Support, Non-U.S. Gov't).

Résumé | Liens | BibTeX | Étiquettes: Amino Acyl/*metabolism RNA-Binding Proteins/*metabolism Saccharomyces cerevisiae/*enzymology/*metabolism Saccharomyces cerevisiae Proteins/*metabolism Transferases/*metabolism, Fungal Glutamate-tRNA Ligase/*metabolism Glutamic Acid/metabolism Mitochondria/*enzymology Protein Binding Protein Transport RNA, KERN Cytoplasm/enzymology Gene Expression Regulation, Transfer, Unité ARN

Bailly, M; Blaise, M; Lorber, B; Thirup, S; Kern, D

Isolation, crystallization and preliminary X-ray analysis of the transamidosome, a ribonucleoprotein involved in asparagine formation Article de journal

Acta Crystallogr F Struct Biol Commun, 65 (Pt 6), p. 577-581, 2009, ISBN: 19478435, (1744-3091 (Electronic) Journal Article Research Support, Non-U.S. Gov't).

Résumé | Liens | BibTeX | Étiquettes: Amino Acyl/genetics/metabolism RNA, Asn/*biosynthesis Ribonucleoproteins/*isolation & purification/*metabolism Scattering, KERN FLORENTZ Asparagine/*biosynthesis Aspartate-tRNA Ligase/*chemistry/genetics/*metabolism Crystallization Data Collection Escherichia coli/genetics Light RNA, Radiation Statistics as Topic Thermus thermophilus/genetics/metabolism Transfer RNA Aminoacylation X-Ray Diffraction, Transfer, Unité ARN

2008

Yao, P; Zhu, B; Jaeger, S; Eriani, G; Wang, E D

Recognition of tRNALeu by Aquifex aeolicus leucyl-tRNA synthetase during the aminoacylation and editing steps Article de journal

Nucleic Acids Res, 36 (8), p. 2728-2738, 2008, ISBN: 18367476, (1362-4962 (Electronic) Journal Article Research Support, Non-U.S. Gov't).

Résumé | Liens | BibTeX | Étiquettes: ERIANI, ERIANI Amino Acids/chemistry Anticodon/chemistry Bacteria/enzymology/genetics Base Sequence Iodine Leucine-tRNA Ligase/chemistry/*metabolism Molecular Sequence Data Mutagenesis Nucleic Acid Conformation Protein Footprinting RNA, Leu/*chemistry/genetics/metabolism Ribonucleases Substrate Specificity *Transfer RNA Aminoacylation, Transfer, Unité ARN

Simonetti, A; Marzi, S; Myasnikov, A G; Fabbretti, A; Yusupov, M; Gualerzi, C O; Klaholz, B P

Structure of the 30S translation initiation complex Article de journal

Nature, 455 (7211), p. 416-420, 2008, ISBN: 18758445, (1476-4687 (Electronic) Journal Article Research Support, Non-U.S. Gov't).

Résumé | Liens | BibTeX | Étiquettes: Messenger/chemistry/genetics/metabolism RNA, Met/chemistry/genetics/metabolism/ultrastructure Ribosome Subunits/chemistry/metabolism/ultrastructure Ribosomes/chemistry/*metabolism/*ultrastructure Thermus thermophilus/*enzymology/genetics/*ultrastructure, Molecular Multiprotein Complexes/*chemistry/genetics/metabolism/*ultrastructure *Peptide Chain Initiation, ROMBY Cryoelectron Microscopy Crystallography, Transfer, Translational Prokaryotic Initiation Factor-1/chemistry/genetics/metabolism/ultrastructure Prokaryotic Initiation Factor-2/chemistry/genetics/metabolism/ultrastructure Protein Conformation RNA, Unité ARN, X-Ray Guanosine Triphosphate/chemistry/metabolism Models

Rederstorff, M; Allamand, V; Guicheney, P; Gartioux, C; Richard, P; Chaigne, D; Krol, A; Lescure, A

Ex vivo correction of selenoprotein N deficiency in rigid spine muscular dystrophy caused by a mutation in the selenocysteine codon Article de journal

Nucleic Acids Res, 36 (1), p. 237-244, 2008, ISBN: 18025044, (1362-4962 (Electronic) Journal Article Research Support, Non-U.S. Gov't).

Résumé | Liens | BibTeX | Étiquettes: Amino Acid-Specific/*genetics Selenocysteine/metabolism Selenoproteins/biosynthesis/*deficiency/*genetics Transgenes, KROL Codon/chemistry *Codon, LESCURE, Nonsense Fibroblasts/metabolism Hela Cells Humans Muscle Proteins/biosynthesis/*deficiency/*genetics Muscular Atrophy, Spinal/*genetics/metabolism RNA, Transfer, Unité ARN

Pujol, C; Bailly, M; Kern, D; Marechal-Drouard, L; Becker, H; Duchene, A M

Dual-targeted tRNA-dependent amidotransferase ensures both mitochondrial and chloroplastic Gln-tRNAGln synthesis in plants Article de journal

Proc Natl Acad Sci U S A, 105 (17), p. 6481-6485, 2008, ISBN: 18441100, (1091-6490 (Electronic) Journal Article Research Support, Non-U.S. Gov't).

Résumé | Liens | BibTeX | Étiquettes: Amino Acyl/*biosynthesis Solanum tuberosum/*enzymology, KERN Arabidopsis/*enzymology Cell Extracts Chloroplasts/*enzymology Cytosol/enzymology Glutamate-tRNA Ligase/metabolism Glutamine/*biosynthesis Mitochondria/*enzymology Nitrogenous Group Transferases/*metabolism Protein Subunits/metabolism Protein Transport RNA, Transfer, Unité ARN

Bonnefond, L; Florentz, C; Giege, R; Rudinger-Thirion, J

Decreased aminoacylation in pathology-related mutants of mitochondrial tRNATyr is associated with structural perturbations in tRNA architecture Article de journal

RNA, 14 (4), p. 641-648, 2008, ISBN: 18268021, (1469-9001 (Electronic) In Vitro Journal Article Research Support, Non-U.S. Gov't).

Résumé | Liens | BibTeX | Étiquettes: FLORENTZ, GIEGE FLORENTZ FRUGIER Base Sequence Humans Mitochondrial Diseases/genetics/metabolism Models, Molecular Molecular Sequence Data Nucleic Acid Conformation *Point Mutation RNA/*chemistry/*genetics/metabolism RNA Stability RNA, Transfer, Tyr/*chemistry/*genetics/metabolism *Transfer RNA Aminoacylation, Unité ARN

Blaise, M; Olieric, V; Sauter, C; Lorber, B; Roy, B; Karmakar, S; Banerjee, R; Becker, H D; Kern, D

Crystal structure of glutamyl-queuosine tRNAAsp synthetase complexed with L-glutamate: structural elements mediating tRNA-independent activation of glutamate and glutamylation of tRNAAsp anticodon Article de journal

J Mol Biol, 381 (5), p. 1224-1237, 2008, ISBN: 18602926, (1089-8638 (Electronic) Journal Article Research Support, Non-U.S. Gov't).

Résumé | Liens | BibTeX | Étiquettes: Asp/*chemistry/genetics Regulatory Sequences, KERN GIEGE FLORENTZ Adenosine Triphosphate/metabolism Amino Acid Sequence Amino Acyl-tRNA Synthetases/*chemistry Anticodon/*metabolism Base Sequence Binding Sites Catalysis Conserved Sequence Crystallography, Molecular Molecular Sequence Data Nucleic Acid Conformation Nucleoside Q/*chemistry Protein Structure, Ribonucleic Acid/*genetics Thermus thermophilus/enzymology, Secondary RNA, Transfer, Unité ARN, X-Ray Escherichia coli/*enzymology Escherichia coli Proteins/*chemistry Glutamic Acid/*chemistry Models

2007

Roy, H; Becker, H D; Mazauric, M H; Kern, D

Structural elements defining elongation factor Tu mediated suppression of codon ambiguity Article de journal

Nucleic Acids Res, 35 (10), p. 3420-3430, 2007, ISBN: 17478519, (1362-4962 (Electronic) Journal Article Research Support, Non-U.S. Gov't).

Résumé | Liens | BibTeX | Étiquettes: Amino Acyl/*chemistry/metabolism RNA, Asn/*chemistry/metabolism RNA, Asp/chemistry/metabolism Thermus thermophilus/genetics *Transfer RNA Aminoacylation, KERN Base Pairing *Codon Escherichia coli Proteins/metabolism Models, Molecular Peptide Elongation Factor Tu/*chemistry/metabolism Protein Binding RNA, Transfer, Unité ARN

2006

Westhof, E

The ribosomal decoding site and antibiotics Article de journal

Biochimie, 88 (8), p. 931-933, 2006, ISBN: 16876930, (0300-9084 (Print) Editorial).

Liens | BibTeX | Étiquettes: Amino Acyl/*metabolism WESTHOF DECEMBRE, Bacterial/*metabolism RNA, Transfer, Unité ARN, WESTHOF Anti-Bacterial Agents/metabolism/*pharmacology Bacteria/*drug effects/genetics/growth & development Binding Sites/drug effects Protein Biosynthesis/drug effects/genetics RNA

Fender, A; Sauter, C; Messmer, M; Putz, J; Giege, R; Florentz, C; Sissler, M

Loss of a primordial identity element for a mammalian mitochondrial aminoacylation system Article de journal

J Biol Chem, 281 (23), p. 15980-15986, 2006, ISBN: 16597625, (0021-9258 (Print) Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Asp/chemistry/genetics/*metabolism Research Support, FLORENTZ, FLORENTZ GIEGE Acylation Base Sequence Humans Kinetics Mutagenesis Nucleic Acid Conformation Plasmids RNA, Non-U.S. Gov't, SISSLER, Transfer, Unité ARN

2005

Jenner, L; Romby, P; Rees, B; Schulze-Briese, C; Springer, M; Ehresmann, C; Ehresmann, B; Moras, D; Yusupova, G; Yusupov, M

Translational operator of mRNA on the ribosome: how repressor proteins exclude ribosome binding Article de journal

Science, 308 (5718), p. 120-123, 2005, ISBN: 15802605, (1095-9203 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: 16S/chemistry/metabolism RNA, Bacterial/*chemistry/metabolism RNA, Messenger/*chemistry/metabolism RNA, Met/chemistry/metabolism *Regulatory Sequences, Molecular Nucleic Acid Conformation *Protein Biosynthesis RNA, Non-U.S. Gov't Ribosomal Proteins/metabolism Ribosomes/*metabolism Thermus thermophilus/genetics/*metabolism Threonine-tRNA Ligase/genetics/metabolism, Ribonucleic Acid Repressor Proteins/*metabolism Research Support, Ribosomal, ROMBY, ROMBY Bacterial Proteins/metabolism Base Pairing Binding Sites Crystallization Crystallography, Transfer, Unité ARN, X-Ray Fourier Analysis Models

Graindorge, J S; Senger, B; Tritch, D; Simos, G; Fasiolo, F

Role of Arc1p in the modulation of yeast glutamyl-tRNA synthetase activity Article de journal

Biochemistry, 44 (4), p. 1344-1352, 2005, ISBN: 15667228, (0006-2960 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: FASIOLO Adenosine Triphosphate/chemistry/metabolism Amino Acid Sequence Aminoacylation Base Sequence Diphosphates/chemistry/metabolism Enzyme Activation Gene Expression Regulation, Fungal Glutamate-tRNA Ligase/isolation & purification/*metabolism Kinetics Molecular Sequence Data Peptide Fragments/chemistry/metabolism Protein Binding Protein Structure, Fungal/genetics/metabolism RNA, Genetic, Glu/genetics/metabolism RNA-Binding Proteins/*chemistry/isolation & purification/metabolism Research Support, Non-U.S. Gov't Saccharomyces cerevisiae/enzymology/genetics/metabolism Saccharomyces cerevisiae Proteins/*chemistry/isolation & purification/metabolism Transcription, Tertiary RNA, Transfer, Unité ARN

Bonnefond, L; Frugier, M; Giege, R; Rudinger-Thirion, J

Human mitochondrial TyrRS disobeys the tyrosine identity rules Article de journal

RNA, 11 (5), p. 558-562, 2005, ISBN: 15840810, (1355-8382 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: ERIANI, FRUGIER, GIEGE FRUGIER Amino Acid Sequence Base Sequence Catalytic Domain Humans Mitochondria/*enzymology Molecular Sequence Data RNA, Non-U.S. Gov't Substrate Specificity Tyrosine/genetics/*metabolism Tyrosine-tRNA Ligase/chemistry/*metabolism, Transfer, Tyr/genetics/*metabolism Research Support, Unité ARN

2004

Costa, A; de Barros, Pais J P; Keith, G; Baranowski, W; Desgres, J

Determination of queuosine derivatives by reverse-phase liquid chromatography for the hypomodification study of Q-bearing tRNAs from various mammal liver cells Article de journal

J Chromatogr B Analyt Technol Biomed Life Sci, 801 (2), p. 237-47, 2004, (1570-0232 Journal Article).

Résumé | BibTeX | Étiquettes: *Chromatography, &, Acyl/chemistry, Amino, Animals, Asn/chemistry, Cells, Chickens, Cultured, derivatives/*analysis, Experimental, Gov't, Hepatocytes/chemistry, high, KEITH, liquid, Liver, Liver/*chemistry, Neoplasms, Non-U.S., Nucleoside, Pressure, purification, Q/*analogs, Rats, RNA, Support, Transfer, Transfer/*chemistry/isolation, tumor

Martineau, Y; Bec, Le C; Monbrun, L; Allo, V; Chiu, I M; Danos, O; Moine, H; Prats, H; Prats, A C

Internal ribosome entry site structural motifs conserved among mammalian fibroblast growth factor 1 alternatively spliced mRNAs Article de journal

Mol Cell Biol, 24 (17), p. 7622-35, 2004, (0270-7306 Journal Article).

Résumé | BibTeX | Étiquettes: (Genetics), *5', *Alternative, *Nucleic, *Promoter, 1/*genetics, Acid, Alignment, Animals, Base, Cell, Conformation, Data, EHRESMANN, Factor, Fibroblast, Gene, Genes, Genetic, Gov't, Growth, Human, Line, Messenger/chemistry/*genetics/metabolism, Mice, Molecular, Muscle, Mutagenesis, Non-U.S., Regions, Ribosomes/*metabolism, RNA, Sequence, Site-Directed, Skeletal/cytology/physiology, Splicing, Structural/genetics, Support, Techniques, Transfer, Untranslated, Vectors

Zheng, Y G; Wei, H; Ling, C; Martin, F; Eriani, G; Wang, E D

Two distinct domains of the beta subunit of Aquifex aeolicus leucyl-tRNA synthetase are involved in tRNA binding as revealed by a three-hybrid selection Article de journal

Nucleic Acids Res, 32 (11), p. 3294-3303, 2004, ISBN: 15208367, (1362-4962 Evaluation Studies Journal Article).

Résumé | Liens | BibTeX | Étiquettes: ERIANI, ERIANI Amino Acid Sequence Binding Sites Gram-Negative Bacteria/*enzymology Kinetics Leucine-tRNA Ligase/*chemistry/genetics/*metabolism Molecular Sequence Data Mutation Protein Structure, Leu/*metabolism Saccharomyces cerevisiae/genetics *Two-Hybrid System Techniques, Tertiary Protein Subunits/chemistry RNA, Transfer, Unité ARN

Théobald-Dietrich, A; Frugier, M; Giege, R; Rudinger-Thirion, J

Atypical archaeal tRNA pyrrolysine transcript behaves towards EF-Tu as a typical elongator tRNA Article de journal

Nucleic Acids Res, 32 (3), p. 1091-1096, 2004, ISBN: 14872064, (1362-4962 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Archaeal/chemistry/*metabolism RNA, ERIANI, FRUGIER, GIEGE Anticodon/metabolism Base Sequence Lysine/*analogs & derivatives/*metabolism Lysine-tRNA Ligase/metabolism Methanosarcina barkeri/genetics Mitochondria/genetics Molecular Sequence Data Nucleic Acid Conformation Peptide Elongation Factor Tu/*metabolism RNA, Non-U.S. Gov't Yeasts/enzymology, Ser/chemistry Selenocysteine/metabolism Support, Transfer, Transfer/chemistry/*metabolism RNA, Unité ARN

Sohm, B; Sissler, M; Park, H; King, M P; Florentz, C

Recognition of human mitochondrial tRNALeu(UUR) by its cognate leucyl-tRNA synthetase Article de journal

J Mol Biol, 339 (1), p. 17-29, 2004, ISBN: 15123417, (0022-2836 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Cultured, FLORENTZ, FLORENTZ *Acylation Base Sequence Comparative Study Human Kinetics Leucine/metabolism Leucine-tRNA Ligase/genetics/*metabolism Mitochondria/*metabolism Molecular Sequence Data Mutation Nucleic Acid Conformation Osteosarcoma/metabolism RNA/*genetics/metabolism RNA, Genetic/*genetics Tumor Cells, Leu/genetics/*metabolism Solutions Substrate Specificity Support, Non-U.S. Gov't Support, P.H.S. Transcription, SISSLER, Transfer, U.S. Gov't, Unité ARN

Sissler, M; Helm, M; Frugier, M; Giege, R; Florentz, C

Aminoacylation properties of pathology-related human mitochondrial tRNA(Lys) variants Article de journal

RNA, 10 (5), p. 841-853, 2004, ISBN: 15100439, (1355-8382 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: ERIANI, FLORENTZ, FLORENTZ GIEGE Acylation Aminoacyltransferases/*genetics Human MERRF Syndrome/genetics Mitochondria/*genetics Mitochondrial Diseases/*genetics Mutation Nucleic Acid Conformation RNA, FRUGIER, Lys/*genetics Sequence Analysis, Non-U.S. Gov't Variation (Genetics), RNA Support, SISSLER, Transfer, Unité ARN

Rangan, P; Masquida, B; Westhof, E; Woodson, S A

Architecture and folding mechanism of the Azoarcus Group I Pre-tRNA Article de journal

J Mol Biol, 339 (1), p. 41-51, 2004, ISBN: 15123419, (0022-2836 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Bacterial/*chemistry/genetics/*metabolism RNA, Ile/chemistry/*genetics Substrate Specificity Support, Molecular Molecular Sequence Data *Nucleic Acid Conformation RNA Precursors/*genetics RNA Splice Sites/genetics RNA Splicing RNA, Non-U.S. Gov't Support, P.H.S., Transfer, U.S. Gov't, Unité ARN, WESTHOF Azoarcus/enzymology/*genetics Base Sequence Binding Sites Exoribonucleases/metabolism Hydroxyl Radical/metabolism Introns/*genetics Magnesium/chemistry Models

Martin, F; Barends, S; Eriani, G

Single amino acid changes in AspRS reveal alternative routes for expanding its tRNA repertoire in vivo Article de journal

Nucleic Acids Res, 32 (13), p. 4081-4089, 2004, ISBN: 15289581, (1362-4962 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Amino Acyl/chemistry/*metabolism Support, ERIANI, ERIANI Amino Acid Substitution Anticodon/metabolism Aspartate-tRNA Ligase/*chemistry/genetics/*metabolism Aspartic Acid/metabolism Binding Sites Models, Molecular Mutation Phenotype Protein Engineering Protein Structure, Non-U.S. Gov't, Tertiary RNA, Transfer, Unité ARN

Levinger, L; Oestreich, I; Florentz, C; Morl, M

A pathogenesis-associated mutation in human mitochondrial tRNALeu(UUR) leads to reduced 3'-end processing and CCA addition Article de journal

J Mol Biol, 337 (3), p. 535-544, 2004, ISBN: 15019775, (0022-2836 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: FLORENTZ, FLORENTZ Human Kinetics Mitochondrial Diseases/*genetics Nucleic Acid Conformation *Point Mutation RNA/*genetics/physiology *RNA 3' End Processing RNA Nucleotidyltransferases/metabolism RNA, Leu/*genetics/physiology Support, Non-U.S. Gov't Support, P.H.S., Transfer, U.S. Gov't, Unité ARN

Fender, A; Sissler, M; Florentz, C; Giege, R

Functional idiosyncrasies of tRNA isoacceptors in cognate and noncognate aminoacylation systems Article de journal

Biochimie, 86 (1), p. 21-29, 2004, ISBN: 14987797, (0300-9084 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Amino Acyl/genetics/*metabolism Saccharomyces cerevisiae Substrate Specificity/genetics/physiology Support, Chemical Molecular Sequence Data Mutation Nucleic Acid Conformation Protein Binding/physiology RNA, FLORENTZ, GIEGE FLORENTZ Amino Acid Activation/physiology Amino Acyl-tRNA Ligases/*metabolism Anticodon Bacterial Proteins/metabolism Base Sequence Cloning, Molecular Computer Simulation Escherichia coli Models, Non-U.S. Gov't Thermus thermophilus, SISSLER, Transfer, Transfer/genetics/*metabolism RNA, Unité ARN

Fender, A; Geslain, R; Eriani, G; Giege, R; Sissler, M; Florentz, C

A yeast arginine specific tRNA is a remnant aspartate acceptor Article de journal

Nucleic Acids Res, 32 (17), p. 5076-5086, 2004, ISBN: 15452274, (1362-4962 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Arg/*chemistry/genetics/metabolism RNA, Asp/*chemistry/genetics/metabolism Saccharomyces cerevisiae/*genetics Sequence Alignment Support, ERIANI, ERIANI FLORENTZ GIEGE Aspartic Acid/metabolism Base Sequence *Evolution, FLORENTZ, Fungal/*chemistry/genetics/metabolism RNA, Molecular Molecular Sequence Data Point Mutation RNA, Non-U.S. Gov't, SISSLER, Transfer, Unité ARN

Dubois, D Y; Blaise, M; Becker, H D; Campanacci, V; Keith, G; Giege, R; Cambillau, C; Lapointe, J; Kern, D

An aminoacyl-tRNA synthetase-like protein encoded by the Escherichia coli yadB gene glutamylates specifically tRNAAsp Article de journal

Proc Natl Acad Sci U S A, 101 (20), p. 7530-7535, 2004, ISBN: 15096594, (0027-8424 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Asp/*metabolism Support, KERN GIEGE Amino Acyl-tRNA Ligases/chemistry/genetics/*metabolism Crystallography, Messenger/metabolism RNA, Non-U.S. Gov't, Tertiary RNA, Transfer, Unité ARN, X-Ray Escherichia coli/enzymology/genetics/*metabolism Escherichia coli Proteins/chemistry/genetics/*metabolism Glutamic Acid/*metabolism Peptide Elongation Factor 2/metabolism Phylogeny Protein Structure

Costa, A; de Barros, Pais J P; Keith, G; Baranowski, W; Desgres, J

Determination of queuosine derivatives by reverse-phase liquid chromatography for the hypomodification study of Q-bearing tRNAs from various mammal liver cells Article de journal

J Chromatogr B Analyt Technol Biomed Life Sci, 801 (2), p. 237-247, 2004, ISBN: 14751792, (1570-0232 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Amino Acyl/chemistry RNA, Asn/chemistry Rats Support, Cultured, Cultured Chickens *Chromatography, Experimental Nucleoside Q/*analogs & derivatives/*analysis RNA, High Pressure Liquid Hepatocytes/chemistry Liver/*chemistry Liver Neoplasms, KEITH Animals Cells, Non-U.S. Gov't Tumor Cells, Transfer, Transfer/*chemistry/isolation & purification RNA, Unité ARN

Campanacci, V; Dubois, D Y; Becker, H D; Kern, D; Spinelli, S; Valencia, C; Pagot, F; Salomoni, A; Grisel, S; Vincentelli, R; Bignon, C; Lapointe, J; Giege, R; Cambillau, C

The Escherichia coli YadB gene product reveals a novel aminoacyl-tRNA synthetase like activity Article de journal

J Mol Biol, 337 (2), p. 273-283, 2004, ISBN: 15003446, (0022-2836 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Amino Acid Support, Bacterial Glutamate-tRNA Ligase/chemistry/genetics/metabolism Glutamic Acid/metabolism Kinetics Ligands Models, Glu/metabolism Sequence Homology, KERN GIEGE Adenosine Monophosphate/metabolism Adenosine Triphosphate/metabolism Amino Acid Sequence Amino Acyl-tRNA Ligases/chemistry/*genetics/*metabolism Carrier Proteins/metabolism Crystallography, Molecular Molecular Sequence Data Neoplasm Proteins/metabolism Nuclear Proteins/metabolism Protein Conformation RNA, Non-U.S. Gov't Thermus thermophilus/enzymology/genetics Zinc/metabolism, Transfer, Unité ARN, X-Ray Escherichia coli/*enzymology/*genetics Escherichia coli Proteins/chemistry/*genetics/*metabolism Genes

Blaise, M; Becker, H D; Keith, G; Cambillau, C; Lapointe, J; Giege, R; Kern, D

A minimalist glutamyl-tRNA synthetase dedicated to aminoacylation of the tRNAAsp QUC anticodon Article de journal

Nucleic Acids Res, 32 (9), p. 2768-2775, 2004, ISBN: 15150343, (1362-4962 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Asp/chemistry/genetics/*metabolism RNA, Bacterial/chemistry/genetics/metabolism RNA, Glu/chemistry/genetics/metabolism Support, KERN Acylation Anticodon/chemistry/genetics/*metabolism Base Sequence Conserved Sequence Escherichia coli/*enzymology/*genetics Evolution Glutamate-tRNA Ligase/*chemistry/genetics/*metabolism Molecular Mimicry Nucleoside Q/genetics/*metabolism Periodic Acid/pharmacology RNA, Non-U.S. Gov't, Transfer, Unité ARN

Ador, L; Jaeger, S; Geslain, R; Martin, F; Cavarelli, J; Eriani, G

Mutation and evolution of the magnesium-binding site of a class II aminoacyl-tRNA synthetase Article de journal

Biochemistry, 43 (22), p. 7028-7037, 2004, ISBN: 15170340, (0006-2960 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Asp/metabolism Saccharomyces cerevisiae/*enzymology Support, ERIANI, ERIANI Acylation Adenosine Triphosphate/metabolism Amino Acid Substitution Aspartate-tRNA Ligase/chemistry/genetics/*metabolism Aspartic Acid/metabolism Binding Sites Catalytic Domain Cell Death Combinatorial Chemistry Techniques Comparative Study *Evolution, Molecular Kinetics Magnesium/*metabolism Mutagenesis, Non-U.S. Gov't Transfection, Site-Directed Mutation/*genetics Peptide Library Protein Binding Protein Conformation RNA, Transfer, Unité ARN

2003

Zhao, M W; Hao, R; Chen, J F; Martin, F; Eriani, G; Wang, E D

Enzymes assembled from Aquifex aeolicus and Escherichia coli leucyl-tRNA synthetases Article de journal

Biochemistry, 42 (25), p. 7694-7700, 2003, ISBN: 12820878, (0006-2960 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Amino Acyl-tRNA Ligases/genetics/*metabolism Escherichia coli/*enzymology Evolution, ERIANI, Horizontal Heat Kinetics Mutation RNA, Leu/*metabolism Structure-Activity Relationship Support, Molecular Gene Transfer, Non-U.S. Gov't, Transfer, Unité ARN

Sohm, B; Frugier, M; Brule, H; Olszak, K; Przykorska, A; Florentz, C

Towards understanding human mitochondrial leucine aminoacylation identity Article de journal

J Mol Biol, 328 (5), p. 995-1010, 2003, ISBN: 12729737, (0022-2836 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Base Sequence Human In Vitro Leucine/*metabolism Leucine-tRNA Ligase/*metabolism Mitochondria/*metabolism Mitochondrial Diseases/genetics/metabolism Molecular Sequence Data Mutation Nucleic Acid Conformation RNA, ERIANI, FLORENTZ, FRUGIER, Leu/chemistry/genetics/*metabolism Recombinant Proteins/genetics/metabolism Solutions Substrate Specificity Support, Non-U.S. Gov't Variation (Genetics), Transfer, Unité ARN

Ryckelynck, M; Giege, R; Frugier, M

Yeast tRNA(Asp) charging accuracy is threatened by the N-terminal extension of aspartyl-tRNA synthetase Article de journal

J Biol Chem, 278 (11), p. 9683-9690, 2003, ISBN: 12486031, (0021-9258 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Amino Acid Motifs Aspartate-tRNA Ligase/*metabolism Aspartic Acid/chemistry Base Sequence Codon Escherichia coli/metabolism Kinetics Molecular Sequence Data Nucleic Acid Conformation Nucleic Acids/chemistry Protein Structure, Asp/*chemistry Support, ERIANI, FRUGIER, Messenger/metabolism RNA, Non-U.S. Gov't Yeasts/metabolism, RYCKELYNCK, Secondary Protein Structure, Tertiary RNA, Transfer, Unité ARN

Romby, P; Springer, M

Bacterial translational control at atomic resolution Article de journal

Trends Genet, 19 (3), p. 155-161, 2003, ISBN: 12615010, (0168-9525 Journal Article Review Review, Tutorial).

Résumé | Liens | BibTeX | Étiquettes: Bacterial *Gene Expression Regulation, Bacterial Models, Base Sequence Conserved Sequence Escherichia coli/*enzymology/*genetics *Gene Expression Regulation, Biological Models, Enzymologic Genes, Genetic, Messenger/genetics/*metabolism RNA, Molecular Molecular Mimicry Nucleic Acid Conformation Operator Regions (Genetics) RNA, Non-U.S. Gov't Threonine-tRNA Ligase/chemistry/*genetics/metabolism *Translation, ROMBY, Thr/*metabolism RNA-Binding Proteins/metabolism Support, Transfer, Unité ARN

Rigourd, M; Goldschmidt, V; Brule, F; Morrow, C D; Ehresmann, B; Ehresmann, C; Marquet, R

Structure-function relationships of the initiation complex of HIV-1 reverse transcription: the case of mutant viruses using tRNA(His) as primer Article de journal

Nucleic Acids Res, 31 (19), p. 5764-5775, 2003, ISBN: 14500840, (1362-4962 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Base Sequence Comparative Study DNA, Genetic, Genetic *Transcription Initiation Site *Transcription, His/*metabolism RNA, MARQUET, Non-U.S. Gov't Templates, Post-Transcriptional RNA, Transfer, Unité ARN, Viral HIV-1/*genetics/metabolism HIV-1 Reverse Transcriptase/metabolism Kinetics Macromolecular Systems Molecular Sequence Data Mutation RNA Probes RNA Processing, Viral/*biosynthesis/genetics Sequence Alignment Structure-Activity Relationship Support, Viral/biosynthesis *Gene Expression Regulation

Rigourd, M; Bec, G; Benas, P; Grice, Le S F; Ehresmann, B; Ehresmann, C; Marquet, R

Effects of tRNA 3 Lys aminoacylation on the initiation of HIV-1 reverse transcription Article de journal

Biochimie, 85 (5), p. 521-525, 2003, ISBN: 12763311, (0300-9084 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Acetyltransferases/metabolism *Acylation Animals Cattle HIV-1/*physiology HIV-1 Reverse Transcriptase/pharmacology RNA/genetics RNA, Genetic/drug effects/*physiology Virus Assembly, Lys/*chemistry/drug effects Support, MARQUET, Non-U.S. Gov't Transcription, Transfer, Unité ARN

Levinger, L; Giege, R; Florentz, C

Pathology-related substitutions in human mitochondrial tRNA(Ile) reduce precursor 3' end processing efficiency in vitro Article de journal

Nucleic Acids Res, 31 (7), p. 1904-1912, 2003, ISBN: 12655007, (1362-4962 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Base Sequence DNA, FLORENTZ, Ile/*genetics/metabolism Support, Mitochondrial/*genetics Endoribonucleases/metabolism Hela Cells Human Kinetics Molecular Sequence Data Mutation RNA Precursors/genetics/metabolism *RNA Processing, Non-U.S. Gov't Support, P.H.S., Post-Transcriptional RNA, Transfer, U.S. Gov't, Unité ARN

Goldschmidt, V; Ehresmann, C; Ehresmann, B; Marquet, R

Does the HIV-1 primer activation signal interact with tRNA3(Lys) during the initiation of reverse transcription? Article de journal

Nucleic Acids Res, 31 (3), p. 850-859, 2003, ISBN: 12560480, (1362-4962 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Amino Acyl/chemistry/*metabolism RNA, Base Sequence Binding Sites DNA Primers DNA, Genetic, MARQUET, Non-U.S. Gov't *Transcription, Transfer, Unité ARN, Viral HIV-1/*genetics HIV-1 Reverse Transcriptase/*metabolism Kinetics Molecular Sequence Data Mutation Nucleic Acid Conformation Oligoribonucleotides RNA, Viral/biosynthesis *Gene Expression Regulation, Viral/chemistry/genetics/metabolism Support

Giege, R

Genetic code expansion Article de journal

Nat Struct Biol, 10 (6), p. 414-416, 2003, ISBN: 12768199, (1072-8368 Comment News).

Liens | BibTeX | Étiquettes: Amino Acyl-tRNA Ligases/*chemistry/genetics/*metabolism Codon *Genetic Code Genetic Engineering/methods Human RNA, Transfer, Transfer/*chemistry/*metabolism RNA, Tyr/chemistry/metabolism Structure-Activity Relationship Tyrosine/chemistry/*genetics/metabolism, Unité ARN

Geslain, R; Martin, F; Camasses, A; Eriani, G

A yeast knockout strain to discriminate between active and inactive tRNA molecules Article de journal

Nucleic Acids Res, 31 (16), p. 4729-4737, 2003, ISBN: 12907713, (1362-4962 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Amino Acyl-tRNA Ligases/metabolism Arginine/genetics/metabolism Base Sequence Blotting, Arg/chemistry/*genetics/metabolism Saccharomyces cerevisiae/*genetics Support, ERIANI, Molecular Hydrogen-Ion Concentration Molecular Sequence Data Mutagenesis, Non-U.S. Gov't, Northern Cloning, Site-Directed Mutation Nucleic Acid Conformation RNA, Transfer, Unité ARN

Geslain, R; Bey, G; Cavarelli, J; Eriani, G

Limited set of amino acid residues in a class Ia aminoacyl-tRNA synthetase is crucial for tRNA binding Article de journal

Biochemistry, 42 (51), p. 15092-15101, 2003, ISBN: 14690419, (0006-2960 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Acylation Alanine/genetics Amino Acids/*chemistry/genetics Anticodon/chemistry/genetics Arginine-tRNA Ligase/*chemistry/classification/genetics Binding Sites/genetics Genes, Arg/*chemistry Saccharomyces cerevisiae/enzymology/genetics/growth & development Saccharomyces cerevisiae Proteins/*chemistry/*genetics Support, ERIANI, Lethal Mutagenesis, Non-U.S. Gov't, Site-Directed Protein Binding/genetics Protein Structure, Tertiary/genetics RNA, Transfer, Unité ARN

Caillet, J; Nogueira, T; Masquida, B; Winter, F; Graffe, M; Dock-Bregeon, A C; Torres-Larios, A; Sankaranarayanan, R; Westhof, E; Ehresmann, B; Ehresmann, C; Romby, P; Springer, M

The modular structure of Escherichia coli threonyl-tRNA synthetase as both an enzyme and a regulator of gene expression Article de journal

Mol Microbiol, 47 (4), p. 961-974, 2003, ISBN: 12581352, (0950-382x Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Amino Acyl/chemistry/metabolism Ribosomes/metabolism Support, Bacterial Genes, Bacterial Macromolecular Systems Models, Bacterial/chemistry/metabolism RNA, Binding Sites Binding, Competitive Escherichia coli/*enzymology/*genetics Evolution, Messenger/metabolism RNA, Molecular Gene Expression Regulation, Molecular Molecular Mimicry Molecular Structure Mutation Operator Regions (Genetics) Protein Structure, Non-U.S. Gov't Threonine-tRNA Ligase/*chemistry/genetics/*metabolism, ROMBY, Tertiary Protein Subunits RNA, Transfer, Unité ARN

2002

Xu, M G; Chen, J F; Martin, F; Zhao, M W; Eriani, G; Wang, E D

Leucyl-tRNA synthetase consisting of two subunits from hyperthermophilic bacteria Aquifex aeolicus Article de journal

J Biol Chem, 277 (44), p. 41590-41596, 2002, ISBN: 12196521, (0021-9258 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Bacteria/*enzymology Binding Sites Circular Dichroism Cloning, ERIANI, Leu Support, Molecular Enzyme Stability Escherichia coli/enzymology Kinetics Leucine-tRNA Ligase/*chemistry/genetics/isolation & purification Protein Subunits RNA, Non-U.S. Gov't, Transfer, Unité ARN

Walter, F; Putz, J; Giege, R; Westhof, E

Binding of tobramycin leads to conformational changes in yeast tRNA(Asp) and inhibition of aminoacylation Article de journal

EMBO J, 21 (4), p. 760-768, 2002, ISBN: 11847123, (0261-4189 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Acylation Base Sequence Carbohydrate Sequence Fluorescence Polarization Molecular Sequence Data *Nucleic Acid Conformation RNA, Asp/chemistry/*metabolism Saccharomyces cerevisiae/*genetics Support, Fungal/chemistry/*metabolism RNA, Non-U.S. Gov't Tobramycin/*metabolism, Transfer, Unité ARN

Goldschmidt, V; Rigourd, M; Ehresmann, C; Grice, Le S F; Ehresmann, B; Marquet, R

Direct and indirect contributions of RNA secondary structure elements to the initiation of HIV-1 reverse transcription Article de journal

J Biol Chem, 277 (45), p. 43233-43242, 2002, ISBN: 12194974, (0021-9258 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Base Sequence DNA Primers DNA Replication HIV-1/*genetics HIV-1 Reverse Transcriptase/*metabolism Human Kinetics Polymerase Chain Reaction RNA, Genetic, Lys/genetics RNA, MARQUET, Non-U.S. Gov't Transcription, Transfer, Unité ARN, Viral/*chemistry/*genetics/metabolism Support

Brule, F; Marquet, R; Rong, L; Wainberg, M A; Roques, B P; Grice, Le S F; Ehresmann, B; Ehresmann, C

Structural and functional properties of the HIV-1 RNA-tRNA(Lys)3 primer complex annealed by the nucleocapsid protein: comparison with the heat-annealed complex Article de journal

RNA, 8 (1), p. 8-15, 2002, ISBN: 11873759, (1355-8382 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Genetic, Genetic Transcription, Lys/*chemistry/genetics/metabolism RNA, MARQUET, Non-U.S. Gov't Templates, Transfer, Unité ARN, Viral/*chemistry/genetics/metabolism Support

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