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2014

Haller, Samantha; Limmer, Stefanie; Ferrandon, Dominique

Assessing Pseudomonas virulence with a nonmammalian host: Drosophila melanogaster Article de journal

Methods Mol. Biol., 1149 , p. 723–740, 2014, ISSN: 1940-6029.

Résumé | Liens | BibTeX | Étiquettes: Animal, Animals, Antimicrobial Cationic Peptides, Biological Assay, Colony Count, Disease Models, ferrandon, Hemolymph, Host-Pathogen Interactions, M3i, Mammals, Microbial, Pseudomonas aeruginosa, Pseudomonas Infections, Reverse Transcriptase Polymerase Chain Reaction, Virulence

2011

Limmer, Stefanie; Haller, Samantha; Drenkard, Eliana; Lee, Janice; Yu, Shen; Kocks, Christine; Ausubel, Frederick M; Ferrandon, Dominique

Pseudomonas aeruginosa RhlR is required to neutralize the cellular immune response in a Drosophila melanogaster oral infection model Article de journal

Proc. Natl. Acad. Sci. U.S.A., 108 (42), p. 17378–17383, 2011, ISSN: 1091-6490.

Résumé | Liens | BibTeX | Étiquettes: Animal, Animals, Bacteremia, Bacterial Proteins, Cellular, Disease Models, ferrandon, Genes, Genetically Modified, Hemolymph, Host-Pathogen Interactions, Immunity, Insect, M3i, Mutation, Oral, Pseudomonas aeruginosa, Pseudomonas Infections, Quorum Sensing, Trans-Activators, Viral, Virulence

2010

Matskevich, Alexey A; Quintin, Jessica; Ferrandon, Dominique

The Drosophila PRR GNBP3 assembles effector complexes involved in antifungal defenses independently of its Toll-pathway activation function Article de journal

Eur. J. Immunol., 40 (5), p. 1244–1254, 2010, ISSN: 1521-4141.

Résumé | Liens | BibTeX | Étiquettes: Agglutination, Animals, Beauveria, Beauveria/immunology, Candida albicans, Candida albicans/immunology, Carrier Proteins, Carrier Proteins/*immunology/pharmacology, Drosophila melanogaster/*immunology/microbiology, Drosophila Proteins/*immunology/pharmacology/physiology, Enzyme Activation, ferrandon, Fungal, Fungi, Fungi/*immunology, Hemolymph, Hemolymph/immunology, M3i, Melanins, Melanins/*physiology, Monophenol Monooxygenase, Monophenol Monooxygenase/physiology, Multiprotein Complexes, Multiprotein Complexes/physiology, Recombinant Fusion Proteins, Recombinant Fusion Proteins/pharmacology, Serpins, Serpins/physiology, Spores, Toll-Like Receptors, Toll-Like Receptors/immunology

2009

Mishima, Yumiko; Quintin, Jessica; Aimanianda, Vishukumar; Kellenberger, Christine; Coste, Franck; Clavaud, Cecile; Hetru, Charles; Hoffmann, Jules A; Latgé, Jean-Paul; Ferrandon, Dominique; Roussel, Alain

The N-terminal domain of Drosophila Gram-negative binding protein 3 (GNBP3) defines a novel family of fungal pattern recognition receptors Article de journal

J. Biol. Chem., 284 (42), p. 28687–28697, 2009, ISSN: 1083-351X.

Résumé | Liens | BibTeX | Étiquettes: Animals, beta-Glucans, Bombyx, Carrier Proteins, Crystallography, ferrandon, Fungal Proteins, Hemolymph, hoffmann, ligands, M3i, Molecular Conformation, Mutagenesis, Polysaccharides, Protein Structure, Secondary, Tertiary, X-Ray

Fraiture, Malou; Baxter, Richard H G; Steinert, Stefanie; Chelliah, Yogarany; Frolet, Cécile; Quispe-Tintaya, Wilber; Hoffmann, Jules A; Blandin, Stéphanie A; Levashina, Elena A

Two mosquito LRR proteins function as complement control factors in the TEP1-mediated killing of Plasmodium Article de journal

Cell Host Microbe, 5 (3), p. 273–284, 2009, ISSN: 1934-6069.

Résumé | Liens | BibTeX | Étiquettes: Animals, Anopheles, APL1, Biological, blandin, Complement System Proteins, Hemolymph, hoffmann, Immunologic Factors, LRIM1, M3i, Models, Plasmodium, Protein Binding, Proteins, TEP1

2007

Nehme, Nadine T; Liégeois, Samuel; Kele, Beatrix; Giammarinaro, Philippe; Pradel, Elizabeth; Hoffmann, Jules A; Ewbank, Jonathan J; Ferrandon, Dominique

A model of bacterial intestinal infections in Drosophila melanogaster Article de journal

PLoS Pathog., 3 (11), p. e173, 2007, ISSN: 1553-7374.

Résumé | Liens | BibTeX | Étiquettes: Animal, Animals, Disease Models, Electron, ferrandon, fluorescence, Hemolymph, hoffmann, Host-Pathogen Interactions, Immunohistochemistry, Intestines, M3i, Microscopy, Reverse Transcriptase Polymerase Chain Reaction, Serratia Infections, Serratia marcescens, Transmission

2006

Leclerc, Vincent; Pelte, Nadège; Chamy, Laure El; Martinelli, Cosimo; Ligoxygakis, Petros; Hoffmann, Jules A; Reichhart, Jean-Marc

Prophenoloxidase activation is not required for survival to microbial infections in Drosophila Article de journal

EMBO Rep., 7 (2), p. 231–235, 2006, ISSN: 1469-221X.

Résumé | Liens | BibTeX | Étiquettes: Animals, Bacterial Infections, Catechol Oxidase, Enzyme Activation, Enzyme Precursors, Gram-Negative Bacteria, Gram-Positive Bacteria, Hemolymph, hoffmann, Immunity, Innate, M3i, Mutation, reichhart, Survival Rate

2003

Gobert, Vanessa; Gottar, Marie; Matskevich, Alexey A; Rutschmann, Sophie; Royet, Julien; Belvin, Marcia; Hoffmann, Jules A; Ferrandon, Dominique

Dual activation of the Drosophila toll pathway by two pattern recognition receptors Article de journal

Science, 302 (5653), p. 2126–2130, 2003, ISSN: 1095-9203.

Résumé | Liens | BibTeX | Étiquettes: Animals, Carrier Proteins, Cell Surface, DNA Transposable Elements, ferrandon, Gene Expression, Genes, Gram-Negative Bacteria, Gram-Positive Bacteria, Hemolymph, hoffmann, Hypocreales, Insect, Insect Proteins, M3i, Mutation, Phenotype, Receptors, Serine Endopeptidases, Toll-Like Receptors

Sabatier, Laurence; Jouanguy, Emmanuelle; Dostert, Catherine; Zachary, Daniel; Dimarcq, Jean-Luc; Bulet, Philippe; Imler, Jean-Luc

Pherokine-2 and -3 Article de journal

European journal of biochemistry / FEBS, 270 (16), p. 3398–3407, 2003, ISSN: 0014-2956.

Résumé | BibTeX | Étiquettes: Animals, Antibody Formation, Base Sequence, Hemolymph, imler, M3i, Mass, Matrix-Assisted Laser Desorption-Ionization, Spectrometry

2002

Ligoxygakis, Petros; Pelte, Nadège; Ji, Chuanyi; Leclerc, Vincent; Duvic, Bernard; Belvin, Marcia; Jiang, Haobo; Hoffmann, Jules A; Reichhart, Jean-Marc

A serpin mutant links Toll activation to melanization in the host defence of Drosophila Article de journal

EMBO J., 21 (23), p. 6330–6337, 2002, ISSN: 0261-4189.

Résumé | BibTeX | Étiquettes: Animals, Cell Surface, Hemolymph, hoffmann, infection, M3i, Melanins, Receptors, reichhart, Serpins, Toll-Like Receptors

Ligoxygakis, Petros; Pelte, Nadège; Hoffmann, Jules A; Reichhart, Jean-Marc

Activation of Drosophila Toll during fungal infection by a blood serine protease Article de journal

Science, 297 (5578), p. 114–116, 2002, ISSN: 1095-9203.

Résumé | Liens | BibTeX | Étiquettes: Animals, Cell Surface, Chromosome Mapping, Escherichia coli, Female, Gene Expression Regulation, Genes, Gram-Positive Cocci, Hemolymph, hoffmann, Hypocreales, Insect, Insect Proteins, M3i, Male, Mutation, Protein Sorting Signals, Protein Structure, Receptors, reichhart, Serine Endopeptidases, Tertiary, Toll-Like Receptors

2001

Michel, T; Reichhart, Jean-Marc; Hoffmann, Jules A; Royet, Julien

Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein Article de journal

Nature, 414 (6865), p. 756–759, 2001, ISSN: 0028-0836.

Résumé | Liens | BibTeX | Étiquettes: Amino Acid, Animals, Anti-Bacterial Agents, Anti-Infective Agents, Bacillus thuringiensis, Carrier Proteins, Cell Surface, Chromosome Mapping, Enterococcus faecalis, Fungi, Genes, Gram-Positive Bacteria, Hemolymph, hoffmann, Humans, Insect, Insect Proteins, M3i, Membrane Glycoproteins, Micrococcus luteus, Mutation, Receptors, reichhart, Sequence Homology, Toll-Like Receptors

1999

Levashina, Elena A; Langley, E; Green, C; Gubb, David; Ashburner, M; Hoffmann, Jules A; Reichhart, Jean-Marc

Constitutive activation of toll-mediated antifungal defense in serpin-deficient Drosophila Article de journal

Science, 285 (5435), p. 1917–1919, 1999, ISSN: 0036-8075.

Résumé | BibTeX | Étiquettes: Animals, Antifungal Agents, Antimicrobial Cationic Peptides, Body Patterning, Cell Surface, Escherichia coli, Genes, Hemolymph, hoffmann, Insect, Insect Proteins, M3i, Membrane Glycoproteins, Micrococcus luteus, Mutagenesis, Peptides, Receptors, Recombinant Fusion Proteins, reichhart, Serine Proteinase Inhibitors, Serpins, Signal Transduction, Toll-Like Receptors, Up-Regulation

Lamberty, M; Ades, S; Uttenweiler-Joseph, S; Brookhart, G; Bushey, D; Hoffmann, Jules A; Bulet, Philippe

Insect immunity. Isolation from the lepidopteran Heliothis virescens of a novel insect defensin with potent antifungal activity Article de journal

J. Biol. Chem., 274 (14), p. 9320–9326, 1999, ISSN: 0021-9258.

Résumé | BibTeX | Étiquettes: Amino Acid, Animals, Antifungal Agents, Capillary, Chromatography, Defensins, Electrophoresis, Escherichia coli, Hemolymph, High Pressure Liquid, hoffmann, Insect Proteins, Larva, Lepidoptera, M3i, Micrococcus luteus, Proteins, Sequence Homology

Lowenberger, C A; Smartt, C T; Bulet, Philippe; Ferdig, M T; Severson, D W; Hoffmann, Jules A; Christensen, B M

Insect immunity: molecular cloning, expression, and characterization of cDNAs and genomic DNA encoding three isoforms of insect defensin in Aedes aegypti Article de journal

Insect Mol. Biol., 8 (1), p. 107–118, 1999, ISSN: 0962-1075.

Résumé | BibTeX | Étiquettes: Aedes, Amino Acid, Animals, Base Sequence, Blotting, Chromosome Mapping, Cloning, Complementary, Defensins, DNA, Gene Expression, Hemolymph, hoffmann, M3i, Molecular, Northern, Protein Isoforms, Proteins, Sequence Homology

Lowenberger, C A; Kamal, S; Chiles, J; Paskewitz, S; Bulet, Philippe; Hoffmann, Jules A; Christensen, B M

Mosquito-Plasmodium interactions in response to immune activation of the vector Article de journal

Exp. Parasitol., 91 (1), p. 59–69, 1999, ISSN: 0014-4894.

Résumé | Liens | BibTeX | Étiquettes: Aedes, Animals, Anopheles, Culicidae, Defensins, Digestive System, Escherichia coli, Female, Genetic, Hemolymph, hoffmann, Insect Vectors, M3i, messenger, Micrococcus luteus, Plasmodium, Plasmodium berghei, Plasmodium gallinaceum, Proteins, Reverse Transcriptase Polymerase Chain Reaction, RNA, Transcription

1998

Uttenweiler-Joseph, S; Moniatte, M; Lagueux, Marie; Dorsselaer, Van A; Hoffmann, Jules A; Bulet, Philippe

Differential display of peptides induced during the immune response of Drosophila: a matrix-assisted laser desorption ionization time-of-flight mass spectrometry study Article de journal

Proc. Natl. Acad. Sci. U.S.A., 95 (19), p. 11342–11347, 1998, ISSN: 0027-8424.

Résumé | BibTeX | Étiquettes: Animals, bacteria, Chromatography, Cloning, Hemolymph, High Pressure Liquid, hoffmann, Immunity, Insect Proteins, M3i, Mass, Matrix-Assisted Laser Desorption-Ionization, messenger, Molecular, Peptides, Protein Precursors, RNA, Sequence Analysis, Spectrometry, Time Factors

1997

Dimarcq, Jean-Luc; Imler, Jean-Luc; Lanot, R; Ezekowitz, Alan R B; Hoffmann, Jules A; Janeway, C A; Lagueux, Marie

Treatment of l(2)mbn Drosophila tumorous blood cells with the steroid hormone ecdysone amplifies the inducibility of antimicrobial peptide gene expression Article de journal

Insect Biochemistry and Molecular Biology, 27 (10), p. 877–886, 1997, ISSN: 0965-1748.

Résumé | BibTeX | Étiquettes: Animals, Bacterial Infections, Cellular, Ecdysone, Gene Expression, Genes, Hemocytes, Hemolymph, hoffmann, imler, Immunity, Insect, M3i, Macrophages, Peptide Biosynthesis, Phagocytosis

1996

Ehret-Sabatier, L; Loew, D; Goyffon, M; Fehlbaum, P; Hoffmann, Jules A; van Dorsselaer, A; Bulet, Philippe

Characterization of novel cysteine-rich antimicrobial peptides from scorpion blood Article de journal

J. Biol. Chem., 271 (47), p. 29537–29544, 1996, ISSN: 0021-9258.

Résumé | BibTeX | Étiquettes: Animals, Anti-Bacterial Agents, Chromatography, Cysteine, Electron, Hemolymph, Hemolysis, High Pressure Liquid, hoffmann, M3i, Mass Spectrometry, Microscopy, Peptides, Scorpions

1995

Bulet, Philippe; Hegy, G; Lambert, J; van Dorsselaer, Alan; Hoffmann, Jules A; Hetru, Charles

Insect immunity. The inducible antibacterial peptide diptericin carries two O-glycans necessary for biological activity Article de journal

Biochemistry, 34 (22), p. 7394–7400, 1995, ISSN: 0006-2960.

Résumé | BibTeX | Étiquettes: Animals, Anti-Bacterial Agents, Carbohydrate Sequence, Carbohydrates, Diptera, Escherichia coli, Glycopeptides, Hemolymph, hoffmann, Insect Hormones, Insect Proteins, Larva, M3i, Mass Spectrometry, Plants, Trisaccharides

1994

Cociancich, S; Dupont, A; Hegy, G; Lanot, R; Holder, F; Hetru, Charles; Hoffmann, Jules A; Bulet, Philippe

Novel inducible antibacterial peptides from a hemipteran insect, the sap-sucking bug Pyrrhocoris apterus Article de journal

Biochem. J., 300 ( Pt 2) , p. 567–575, 1994, ISSN: 0264-6021.

Résumé | BibTeX | Étiquettes: Amino Acid, Animals, Anti-Bacterial Agents, Antimicrobial Cationic Peptides, Blood Proteins, Chromatography, Defensins, Gas Chromatography-Mass Spectrometry, Gel, Gram-Negative Bacteria, Gram-Positive Bacteria, Hemiptera, Hemolymph, hoffmann, Insect Proteins, M3i, Peptides, Sequence Homology

1992

Bulet, Philippe; Cociancich, S; Reuland, M; Sauber, F; Bischoff, R; Hegy, G; Dorsselaer, Van A; Hetru, Charles; Hoffmann, Jules A

A novel insect defensin mediates the inducible antibacterial activity in larvae of the dragonfly Aeschna cyanea (Paleoptera, Odonata) Article de journal

Eur. J. Biochem., 209 (3), p. 977–984, 1992, ISSN: 0014-2956.

Résumé | BibTeX | Étiquettes: Animals, Anti-Bacterial Agents, Antimicrobial Cationic Peptides, Blood Bactericidal Activity, Blood Proteins, Defensins, Hemolymph, hoffmann, Insect Proteins, insects, Larva, M3i, Mass Spectrometry, Peptides

1991

Bulet, Philippe; Cociancich, S; Dimarcq, Jean-Luc; Lambert, J; Reichhart, Jean-Marc; Hoffmann, Danièle; Hetru, Charles; Hoffmann, Jules A

Insect immunity. Isolation from a coleopteran insect of a novel inducible antibacterial peptide and of new members of the insect defensin family Article de journal

J. Biol. Chem., 266 (36), p. 24520–24525, 1991, ISSN: 0021-9258.

Résumé | BibTeX | Étiquettes: Animals, Antibody Formation, Beetles, Blood Bactericidal Activity, Blood Proteins, Chromatography, Defensins, Hemolymph, High Pressure Liquid, hoffmann, Insect Hormones, Insect Proteins, M3i, reichhart

Lepage, P; Bitsch, F; Roecklin, D; Keppi, E; Dimarcq, Jean-Luc; Reichhart, Jean-Marc; Hoffmann, Jules A; Roitsch, C; Dorsselaer, Van A

Determination of disulfide bridges in natural and recombinant insect defensin A Article de journal

Eur. J. Biochem., 196 (3), p. 735–742, 1991, ISSN: 0014-2956.

Résumé | BibTeX | Étiquettes: Animals, Blood Proteins, Defensins, Diptera, Disulfides, Hemolymph, hoffmann, M3i, Mass Spectrometry, Recombinant Proteins, reichhart

1977

Hoffmann, Danièle; Brehelin, M; Hoffmann, Jules A

First results of the antibacterial defense reactions of Locusta migratoria larva and imago Article de journal

Ann Parasitol Hum Comp, 52 (1), p. 87–88, 1977, ISSN: 0003-4150.

BibTeX | Étiquettes: Animals, Bacillus thuringiensis, bacteria, Cellular, Grasshoppers, Hematopoietic System, Hemocytes, Hemolymph, hoffmann, Immunity, Larva, M3i, Muramidase

1976

Lagueux, Marie; Hirn, M; de Reggi, M; Hoffmann, Jules A

Ecdysteroid levels and ovarian development in adult female Locust migratoria Article de journal

C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat., 282 (12), p. 1187–1190, 1976.

Résumé | BibTeX | Étiquettes: Adipose Tissue, Animals, Castration, Female, Grasshoppers, Hemolymph, hoffmann, Invertebrate Hormones, M3i, Neurosecretory Systems, Oogenesis, Ovary, Oviposition

1975

Zachary, Daniel; Bréhelin, M; Hoffmann, Jules A

Role of the “thrombocytoids” in capsule formation in the dipteran Calliphora erythrocephala Article de journal

Cell Tissue Res., 162 (3), p. 343–348, 1975, ISSN: 0302-766X.

Résumé | BibTeX | Étiquettes: Agglutination, Animals, Diptera, Foreign Bodies, Hemolymph, hoffmann, M3i, Phagocytosis

1974

Goltzené, F; Hoffmann, Jules A

Control of haemolymph protein synthesis and oocyte maturation by the corpora allata in female adults of locusta migratoria (Orthoptera): role of the blood-forming tissue Article de journal

Gen. Comp. Endocrinol., 22 (4), p. 489–498, 1974, ISSN: 0016-6480.

BibTeX | Étiquettes: Animals, Disc, Electrophoresis, Female, Grasshoppers, Hematopoietic System, Hemolymph, hoffmann, M3i, Ovum, Protein Biosynthesis, Radiation Effects

1973

Zachary, Daniel; Hoffmann, Jules A

The haemocytes of Calliphora erythrocephala (Meig.) (Diptera) Article de journal

Z Zellforsch Mikrosk Anat, 141 (1), p. 55–73, 1973, ISSN: 0340-0336.

BibTeX | Étiquettes: Animals, Cell Count, Cell Nucleus, Diptera, Electron, Endoplasmic Reticulum, Hemolymph, Hemostasis, hoffmann, Inclusion Bodies, Larva, Lipids, Lysosomes, M3i, Microscopy, mitochondria, Phase-Contrast, Pupa, Radiation Effects

1972

Zachary, Daniel; Hoffmann, Jules A; Porte, A

A new type of blood cell (the thrombocytoid) in Calliphora erythrocephala Article de journal

C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat., 275 (3), p. 393–395, 1972.

BibTeX | Étiquettes: Animals, Blood Cells, Blood Platelets, Cell Membrane, Cell Nucleus, Cytoplasm, Diptera, Electron, Hemolymph, hoffmann, M3i, Microscopy, Phase-Contrast

1970

Hoffmann, Jules A

Endocrine regulation of production and differentiation of hemocytes in an orthopteran insect: Locusta migratoria migratoroides Article de journal

Gen. Comp. Endocrinol., 15 (2), p. 198–219, 1970, ISSN: 0016-6480.

BibTeX | Étiquettes: Animals, Biological, Blood Cells, Electrocoagulation, Female, Hemolymph, hoffmann, insects, M3i, Male, Metamorphosis, Microscopy, Neurosecretory Systems, Phase-Contrast

Hoffmann, Jules A; Porte, A; Joly, P

On the localization of phenol-oxidase activity in coagulocytes of Locusta migratoria L. (Orthoptera) Article de journal

C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat., 270 (4), p. 629–631, 1970.

BibTeX | Étiquettes: Animals, Catechol Oxidase, Hemolymph, hoffmann, insects, M3i, Tanning