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2009

Shia, Alice K H; Glittenberg, Marcus; Thompson, Gavin; Weber, Alexander N R; Reichhart, Jean-Marc; Ligoxygakis, Petros

Toll-dependent antimicrobial responses in Drosophila larval fat body require Spätzle secreted by haemocytes Article de journal

J. Cell. Sci., 122 (Pt 24), p. 4505–4515, 2009, ISSN: 1477-9137.

Résumé | Liens | BibTeX | Étiquettes: Animals, Enterococcus faecalis, Escherichia coli, Fat Body, Hemocytes, Larva, M3i, reichhart, Toll-Like Receptors

2006

Bischoff, Vincent; Vignal, Cécile; Duvic, Bernard; Boneca, Ivo G; Hoffmann, Jules A; Royet, Julien

Downregulation of the Drosophila immune response by peptidoglycan-recognition proteins SC1 and SC2 Article de journal

PLoS Pathog., 2 (2), p. e14, 2006, ISSN: 1553-7374.

Résumé | Liens | BibTeX | Étiquettes: Animals, Antimicrobial Cationic Peptides, bacteria, Carrier Proteins, Down-Regulation, hoffmann, Larva, M3i, RNA Interference, Signal Transduction

2005

Irving, Phil; Ubeda, Jean-Michel; Doucet, Daniel; Troxler, Laurent; Lagueux, Marie; Zachary, Daniel; Hoffmann, Jules A; Hetru, Charles; Meister, Marie

New insights into Drosophila larval haemocyte functions through genome-wide analysis Article de journal

Cell. Microbiol., 7 (3), p. 335–350, 2005, ISSN: 1462-5814.

Résumé | Liens | BibTeX | Étiquettes: Animals, bioinformatic, Catechol Oxidase, Cell Lineage, Enzyme Precursors, Escherichia coli, Fat Body, Gene Expression Profiling, Genome, Hemocytes, hoffmann, Integrin alpha Chains, Integrins, Larva, M3i, Micrococcus luteus

2002

Munier, Anne-Isabelle; Doucet, Daniel; Perrodou, Emmanuel; Zachary, Daniel; Meister, Marie; Hoffmann, Jules A; Janeway, Charles A; Lagueux, Marie

PVF2, a PDGF/VEGF-like growth factor, induces hemocyte proliferation in Drosophila larvae Article de journal

EMBO Rep., 3 (12), p. 1195–1200, 2002, ISSN: 1469-221X.

Résumé | Liens | BibTeX | Étiquettes: Animals, Antibodies, Blotting, Cell Differentiation, Hemocytes, hoffmann, Immunohistochemistry, Larva, ligands, M3i, Platelet-Derived Growth Factor, Receptors, Vascular Endothelial Growth Factor, Western

Kambris, Zakaria; Hoffmann, Jules A; Imler, Jean-Luc; Capovilla, Maria

Tissue and stage-specific expression of the Tolls in Drosophila embryos Article de journal

Gene expression patterns: GEP, 2 (3-4), p. 311–317, 2002, ISSN: 1567-133X.

Résumé | BibTeX | Étiquettes: Animals, Blotting, Cell Surface, Gene Expression Profiling, hoffmann, imler, Larva, M3i, Multigene Family, Northern, Receptors, Toll-Like Receptors

Duvic, Bernard; Hoffmann, Jules A; Meister, Marie; Royet, Julien

Notch signaling controls lineage specification during Drosophila larval hematopoiesis Article de journal

Curr. Biol., 12 (22), p. 1923–1927, 2002, ISSN: 0960-9822.

Résumé | BibTeX | Étiquettes: Animals, Cell Differentiation, Hematopoiesis, hoffmann, Larva, Lymphoid Tissue, M3i, Membrane Proteins, Notch, Receptors, Signal Transduction

Ligoxygakis, Petros; Bulet, Philippe; Reichhart, Jean-Marc

Critical evaluation of the role of the Toll-like receptor 18-Wheeler in the host defense of Drosophila Article de journal

EMBO Rep., 3 (7), p. 666–673, 2002, ISSN: 1469-221X.

Résumé | Liens | BibTeX | Étiquettes: Animals, Anti-Bacterial Agents, Antimicrobial Cationic Peptides, Cell Adhesion Molecules, Fat Body, Gene Expression Regulation, Genes, Immunohistochemistry, Immunologic, Insect, Insect Proteins, Larva, M3i, Mass, Matrix-Assisted Laser Desorption-Ionization, Membrane Proteins, Receptors, reichhart, Reporter, Spectrometry, Transgenes

2000

Basset, A; Khush, R S; Braun, A; Gardan, L; Boccard, F; Hoffmann, Jules A; Lemaitre, Bruno

The phytopathogenic bacteria Erwinia carotovora infects Drosophila and activates an immune response Article de journal

Proc. Natl. Acad. Sci. U.S.A., 97 (7), p. 3376–3381, 2000, ISSN: 0027-8424.

Résumé | Liens | BibTeX | Étiquettes: Animals, Bacterial, Gene Expression Regulation, Genetically Modified, hoffmann, Insect Proteins, Larva, M3i, Pectobacterium carotovorum

Imler, Jean-Luc; Hoffmann, Jules A

Toll and Toll-like proteins: an ancient family of receptors signaling infection Article de journal

Reviews in Immunogenetics, 2 (3), p. 294–304, 2000, ISSN: 1398-1714.

Résumé | BibTeX | Étiquettes: Adaptor Proteins, Animals, Antigens, Autoantigens, CD14, Cell Adhesion Molecules, Cell Surface, Differentiation, DNA-Binding Proteins, Gene Expression Regulation, hoffmann, I-kappa B Proteins, imler, Immunity, Immunologic, infection, Innate, Insect Proteins, Interleukin-1 Receptor-Associated Kinases, Knockout, Larva, Lipopolysaccharides, M3i, Mammals, MAP Kinase Signaling System, Membrane Glycoproteins, Membrane Proteins, Mice, Multigene Family, Myeloid Differentiation Factor 88, NF-kappa B, peptidoglycan, Phosphorylation, Post-Translational, Protein Kinases, Protein Processing, Protein Structure, Receptors, Recombinant Fusion Proteins, Signal Transducing, Signal Transduction, Teichoic Acids, Tertiary, Toll-Like Receptor 4, Toll-Like Receptor 5, Toll-Like Receptor 6, Toll-Like Receptor 9, Toll-Like Receptors, Ubiquitins

1999

Manfruelli, P; Reichhart, Jean-Marc; Steward, R; Hoffmann, Jules A; Lemaitre, Bruno

A mosaic analysis in Drosophila fat body cells of the control of antimicrobial peptide genes by the Rel proteins Dorsal and DIF Article de journal

EMBO J., 18 (12), p. 3380–3391, 1999, ISSN: 0261-4189.

Résumé | Liens | BibTeX | Étiquettes: Animals, Anti-Infective Agents, Cell Surface, Clone Cells, DNA-Binding Proteins, Fat Body, Female, Gene Expression Regulation, Genes, hoffmann, Insect, Insect Proteins, Larva, M3i, Male, Membrane Glycoproteins, Mosaicism, Mutation, Nuclear Proteins, Phosphoproteins, Receptors, reichhart, Reporter, Signal Transduction, Toll-Like Receptors, Transcription Factors

Lamberty, M; Ades, S; Uttenweiler-Joseph, S; Brookhart, G; Bushey, D; Hoffmann, Jules A; Bulet, Philippe

Insect immunity. Isolation from the lepidopteran Heliothis virescens of a novel insect defensin with potent antifungal activity Article de journal

J. Biol. Chem., 274 (14), p. 9320–9326, 1999, ISSN: 0021-9258.

Résumé | BibTeX | Étiquettes: Amino Acid, Animals, Antifungal Agents, Capillary, Chromatography, Defensins, Electrophoresis, Escherichia coli, Hemolymph, High Pressure Liquid, hoffmann, Insect Proteins, Larva, Lepidoptera, M3i, Micrococcus luteus, Proteins, Sequence Homology

1998

Braun, A; Hoffmann, Jules A; Meister, Marie

Analysis of the Drosophila host defense in domino mutant larvae, which are devoid of hemocytes Article de journal

Proc. Natl. Acad. Sci. U.S.A., 95 (24), p. 14337–14342, 1998, ISSN: 0027-8424.

Résumé | BibTeX | Étiquettes: Adipose Tissue, Animals, Candida, Escherichia coli, Fungal, Genotype, Hemocytes, hoffmann, Larva, M3i, Melanins, Micrococcus luteus, Spores

Ferrandon, Dominique; Jung, Alain C; Criqui, M; Lemaitre, Bruno; Uttenweiler-Joseph, S; Michaut, Lydia; Reichhart, Jean-Marc; Hoffmann, Jules A

A drosomycin-GFP reporter transgene reveals a local immune response in Drosophila that is not dependent on the Toll pathway Article de journal

EMBO J., 17 (5), p. 1217–1227, 1998, ISSN: 0261-4189.

Résumé | Liens | BibTeX | Étiquettes: Animals, bacteria, Cell Surface, Developmental, Digestive System, Epithelium, Fat Body, Female, ferrandon, Fungal, Gene Expression Regulation, Genes, Green Fluorescent Proteins, hoffmann, Insect Proteins, Larva, Luminescent Proteins, M3i, Male, Membrane Glycoproteins, Organ Specificity, Receptors, reichhart, Reporter, Respiratory System, Spores, Toll-Like Receptors, Trachea, Transgenes

Nicolas, E; Reichhart, Jean-Marc; Hoffmann, Jules A; Lemaitre, Bruno

In vivo regulation of the IkappaB homologue cactus during the immune response of Drosophila Article de journal

J. Biol. Chem., 273 (17), p. 10463–10469, 1998, ISSN: 0021-9258.

Résumé | BibTeX | Étiquettes: Animals, Cell Surface, DNA-Binding Proteins, Gene Expression Regulation, hoffmann, Insect Proteins, Larva, M3i, Membrane Glycoproteins, Phosphoproteins, Proto-Oncogene Proteins, Receptors, reichhart, Signal Transduction, Toll-Like Receptors, Transcription Factor RelB, Transcription Factors

Levashina, Elena A; Ohresser, S; Lemaitre, Bruno; Imler, Jean-Luc

Two distinct pathways can control expression of the gene encoding the Drosophila antimicrobial peptide metchnikowin Article de journal

Journal of Molecular Biology, 278 (3), p. 515–527, 1998, ISSN: 0022-2836.

Résumé | Liens | BibTeX | Étiquettes: Animals, Anti-Infective Agents, Antimicrobial Cationic Peptides, Base Sequence, Cloning, Gene Expression Regulation, Genes, Genetic, Genetically Modified, Glycopeptides, imler, Insect, Insect Proteins, Larva, M3i, Molecular, Mutation, Peptides, Promoter Regions, Recombinant Fusion Proteins, Reporter, Restriction Mapping, Transcription

1996

Richman, A M; Bulet, Philippe; Hetru, Charles; Barillas-Mury, Carolina; Hoffmann, Jules A; Kafalos, Fotis C

Inducible immune factors of the vector mosquito Anopheles gambiae: biochemical purification of a defensin antibacterial peptide and molecular cloning of preprodefensin cDNA Article de journal

Insect Mol. Biol., 5 (3), p. 203–210, 1996, ISSN: 0962-1075.

Résumé | BibTeX | Étiquettes: Amino Acid, Animals, Anopheles, Base Sequence, Blood Bactericidal Activity, Blood Proteins, Cloning, Complementary, Defensins, DNA, Escherichia coli, Female, Gene Expression, Genes, hoffmann, Insect, Insect Vectors, Larva, M3i, Micrococcus luteus, Molecular, Sequence Homology

1995

Bulet, Philippe; Hegy, G; Lambert, J; van Dorsselaer, Alan; Hoffmann, Jules A; Hetru, Charles

Insect immunity. The inducible antibacterial peptide diptericin carries two O-glycans necessary for biological activity Article de journal

Biochemistry, 34 (22), p. 7394–7400, 1995, ISSN: 0006-2960.

Résumé | BibTeX | Étiquettes: Animals, Anti-Bacterial Agents, Carbohydrate Sequence, Carbohydrates, Diptera, Escherichia coli, Glycopeptides, Hemolymph, hoffmann, Insect Hormones, Insect Proteins, Larva, M3i, Mass Spectrometry, Plants, Trisaccharides

1994

Dimarcq, Jean-Luc; Hoffmann, Danièle; Meister, Marie; Bulet, Philippe; Lanot, R; Reichhart, Jean-Marc; Hoffmann, Jules A

Characterization and transcriptional profiles of a Drosophila gene encoding an insect defensin. A study in insect immunity Article de journal

Eur. J. Biochem., 221 (1), p. 201–209, 1994, ISSN: 0014-2956.

Résumé | BibTeX | Étiquettes: Animals, Base Sequence, Blood Proteins, Chromosome Mapping, Cloning, Complementary, Defensins, DNA, Gene Expression, Genetic, Gram-Positive Bacteria, hoffmann, Larva, M3i, Molecular, Molecular Structure, Nucleic Acid, Protein Precursors, Regulatory Sequences, reichhart, Transcription

1993

Georgel, Philippe; Meister, Marie; Kappler, Christine; Lemaitre, Bruno; Reichhart, Jean-Marc; Hoffmann, Jules A

Insect immunity: the diptericin promoter contains multiple functional regulatory sequences homologous to mammalian acute-phase response elements Article de journal

Biochem. Biophys. Res. Commun., 197 (2), p. 508–517, 1993, ISSN: 0006-291X.

Résumé | Liens | BibTeX | Étiquettes: Acute-Phase Proteins, Animals, Anti-Infective Agents, Base Sequence, Cell Line, Deoxyribonuclease I, DNA-Binding Proteins, Genetic, hoffmann, Insect Hormones, Insect Proteins, Larva, M3i, Mammals, NF-kappa B, Nucleic Acid, Oligonucleotide Probes, Polymerase Chain Reaction, Promoter Regions, Regulatory Sequences, reichhart

1992

Bulet, Philippe; Cociancich, S; Reuland, M; Sauber, F; Bischoff, R; Hegy, G; Dorsselaer, Van A; Hetru, Charles; Hoffmann, Jules A

A novel insect defensin mediates the inducible antibacterial activity in larvae of the dragonfly Aeschna cyanea (Paleoptera, Odonata) Article de journal

Eur. J. Biochem., 209 (3), p. 977–984, 1992, ISSN: 0014-2956.

Résumé | BibTeX | Étiquettes: Animals, Anti-Bacterial Agents, Antimicrobial Cationic Peptides, Blood Bactericidal Activity, Blood Proteins, Defensins, Hemolymph, hoffmann, Insect Proteins, insects, Larva, M3i, Mass Spectrometry, Peptides

1990

Dimarcq, Jean-Luc; Zachary, Daniel; Hoffmann, Jules A; Hoffmann, Danièle; Reichhart, Jean-Marc

Insect immunity: expression of the two major inducible antibacterial peptides, defensin and diptericin, in Phormia terranovae Article de journal

EMBO J., 9 (8), p. 2507–2515, 1990, ISSN: 0261-4189.

Résumé | BibTeX | Étiquettes: Animals, Anti-Bacterial Agents, Base Sequence, Blood Proteins, Cloning, Defensins, Diptera, Gene Expression, hoffmann, Insect Hormones, Insect Proteins, Larva, M3i, Molecular, Nucleic Acid Hybridization, Oligonucleotide Probes, Protein Conformation, reichhart

1988

Dimarcq, Jean-Luc; Keppi, E; Dunbar, B; Lambert, J; Reichhart, Jean-Marc; Hoffmann, Danièle; Rankine, S M; Fothergill, J E; Hoffmann, Jules A

Insect immunity. Purification and characterization of a family of novel inducible antibacterial proteins from immunized larvae of the dipteran Phormia terranovae and complete amino-acid sequence of the predominant member, diptericin A Article de journal

Eur. J. Biochem., 171 (1-2), p. 17–22, 1988, ISSN: 0014-2956.

Résumé | BibTeX | Étiquettes: Amino Acids, Animals, Anti-Bacterial Agents, Diptera, Escherichia coli, hoffmann, Insect Hormones, Insect Proteins, Isoelectric Point, Larva, M3i, reichhart

1985

Meister, Marie F; Dimarcq, Jean-Luc; Kappler, Christine; Hetru, Charles; Lagueux, Marie; Lanot, R; Luu, B; Hoffmann, Jules A

Conversion of a radiolabelled ecdysone precursor, 2,22,25-trideoxyecdysone, by embryonic and larval tissues of Locusta migratoria Article de journal

Mol. Cell. Endocrinol., 41 (1), p. 27–44, 1985, ISSN: 0303-7207.

Résumé | BibTeX | Étiquettes: Abdomen, Animals, Cholestenones, Chromatography, Ecdysone, Epidermis, Fat Body, Grasshoppers, Head, High Pressure Liquid, hoffmann, Hydroxylation, Larva, M3i, Malpighian Tubules, Thorax

1980

Zachary, Daniel; Hoffmann, Jules A

Endocrine control of the metamorphosis of the larval muscles in Calliphora erythrocephala (Diptera): in vitro studies of the role of ecdysteroids Article de journal

Dev. Biol., 80 (1), p. 235–247, 1980, ISSN: 0012-1606.

BibTeX | Étiquettes: Animals, Biological, Diptera, Ecdysone, Ecdysterone, hoffmann, Larva, M3i, Metamorphosis, Muscles, Organ Culture Techniques

1977

Hoffmann, Danièle; Brehelin, M; Hoffmann, Jules A

First results of the antibacterial defense reactions of Locusta migratoria larva and imago Article de journal

Ann Parasitol Hum Comp, 52 (1), p. 87–88, 1977, ISSN: 0003-4150.

BibTeX | Étiquettes: Animals, Bacillus thuringiensis, bacteria, Cellular, Grasshoppers, Hematopoietic System, Hemocytes, Hemolymph, hoffmann, Immunity, Larva, M3i, Muramidase

1976

Feyereisen, R; Lagueux, Marie; Hoffmann, Jules A

Dynamics of ecdysone metabolism after ingestion and injection in Locusta migratoria Article de journal

Gen. Comp. Endocrinol., 29 (3), p. 319–327, 1976, ISSN: 0016-6480.

BibTeX | Étiquettes: Animals, Ecdysone, Grasshoppers, hoffmann, Hydroxylation, Injections, Intestines, Larva, M3i, Malpighian Tubules, Oral

1975

Feyereisen, R; Lagueux, Marie; Hoffmann, Jules A

The hemolymphatic transport of molting hormone during the development of Locusta migratoria L Article de journal

C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat., 280 (14), p. 1709–1712, 1975.

Résumé | BibTeX | Étiquettes: Age Factors, Animals, Carrier Proteins, Chromatography, Ecdysone, Ecdysterone, Gel, Grasshoppers, Hematopoietic System, hoffmann, Larva, M3i, Neurosecretory Systems, Protein Binding, Time Factors

Hoffmann, Jules A; Koolman, J; Beyler, C

The role of the prothoracic glands in the production of ecdysone during the last larval instar of Locusta migratoria L Article de journal

C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat., 280 (6), p. 733–736, 1975.

Résumé | BibTeX | Étiquettes: Animals, Cholesterol, Ecdysone, Grasshoppers, hoffmann, Larva, M3i

1974

Hoffmann, Jules A; Weins, M J

Active protein synthesis in the prothoracic glands and ecdysone titer in the permanent larvae of Locusta migratoria after selective irradiation of hematopoietic tissue Article de journal

Experientia, 30 (7), p. 821–822, 1974, ISSN: 0014-4754.

BibTeX | Étiquettes: Animals, Ecdysone, Grasshoppers, Hematopoietic System, hoffmann, Larva, Leucine, M3i, Protein Biosynthesis, Radiation Effects, Tritium

Hoffmann, Jules A; Koolman, J; Karlson, P; Joly, P

Molting hormone titer and metabolic fate of injected ecdysone during the fifth larval instar and in adults of Locusta migratoria (Orthoptera) Article de journal

Gen. Comp. Endocrinol., 22 (1), p. 90–97, 1974, ISSN: 0016-6480.

BibTeX | Étiquettes: Age Factors, Animals, Chromatography, Ecdysone, Feces, Grasshoppers, hoffmann, Hydroxylation, Invertebrate Hormones, Larva, M3i, Thin Layer, Time Factors, Tritium

1973

Koolman, J; Hoffmann, Jules A; Karlson, P

Sulphage esters as inactivation products of ecdysone in Locusta migratoria Article de journal

Hoppe-Seyler's Z. Physiol. Chem., 354 (9), p. 1043–1048, 1973, ISSN: 0018-4888.

BibTeX | Étiquettes: Animals, Biological, Cattle, Chromatography, Ecdysone, Electrophoresis, Esterases, Glucosidases, Glucuronidase, Grasshoppers, hoffmann, Hydrogen-Ion Concentration, Hydrolysis, Ion Exchange, Isotope Labeling, Kinetics, Larva, Liver, M3i, Metamorphosis, Paper, Plants, Saccharomyces cerevisiae, Snails, Sulfatases, Sulfur Radioisotopes, Sulfuric Acids, Swine, Thin Layer, Time Factors, Tritium

Zachary, Daniel; Hoffmann, Jules A

The haemocytes of Calliphora erythrocephala (Meig.) (Diptera) Article de journal

Z Zellforsch Mikrosk Anat, 141 (1), p. 55–73, 1973, ISSN: 0340-0336.

BibTeX | Étiquettes: Animals, Cell Count, Cell Nucleus, Diptera, Electron, Endoplasmic Reticulum, Hemolymph, Hemostasis, hoffmann, Inclusion Bodies, Larva, Lipids, Lysosomes, M3i, Microscopy, mitochondria, Phase-Contrast, Pupa, Radiation Effects

Joly, L; Weins, M J; Hoffmann, Jules A; Porte, A

Development of the prothoracic glands of permanent larvae of Locusta migratoria obtained by selective irradiation of the hemocytopoietic tissue Article de journal

Z Zellforsch Mikrosk Anat, 137 (3), p. 387–397, 1973, ISSN: 0340-0336.

BibTeX | Étiquettes: Age Factors, Animals, Biological, Ecdysone, Electron, Endocrine Glands, Golgi Apparatus, Grasshoppers, hoffmann, Larva, M3i, Metamorphosis, Microscopy, Radiation Effects, ribosomes