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Publications

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2020

Trachman, 3rd R J; Cojocaru, R; Wu, D; Piszczek, G; Ryckelynck, M; Unrau, P J; Ferré-D'Amaré, A R

Structure-Guided Engineering of the Homodimeric Mango-IV Fluorescence Turn-on Aptamer Yields an RNA FRET Pair Article de journal

Structure, 28 (7), p. 776-785.e773, 2020, ISBN: 32386573.

Résumé | Liens | BibTeX | Étiquettes: RYCKELYNCK, RYCKELYNCK RNA aptamer RNA fluorescence RNA structure fluorescent dye structure-guided engineering, Unité ARN

Pernod, K; Schaeffer, L; Chicher, J; Hok, E; Rick, C; Geslain, R; Eriani, G; Westhof, E; Ryckelynck, M; Martin, F

The Nature of the Purine at Position 34 in tRNAs of 4-codon Boxes Is Correlated With Nucleotides at Positions 32 and 38 to Maintain Decoding Fidelity Article de journal

Nucleic Acids Res, 48 (11), p. 6170-6183, 2020, ISBN: 32266934.

Résumé | Liens | BibTeX | Étiquettes: ERIANI, ERIANI RYCKELYNCK WESTHOF, RYCKELYNCK, Unité ARN, WESTHOF

Bouhedda, F; Fam, K T; Collot, M; Autour, A; Marzi, S; Klymchenko, A; Ryckelynck, M

A dimerization-based fluorogenic dye-aptamer module for RNA imaging in live cells Article de journal

Nat Chem Biol, 16 (1), p. 69-76, 2020, ISBN: 31636432.

Résumé | Liens | BibTeX | Étiquettes: RYCKELYNCK, Unité ARN

2019

Trachman, 3rd R J; Autour, A; Jeng, S C Y; Abdolahzadeh, A; Andreoni, A; Cojocaru, R; Garipov, R; Dolgosheina, E V; Knutson, J R; Ryckelynck, M; Unrau, P J; Ferré-D'Amaré, A R

Structure and functional reselection of the Mango-III fluorogenic RNA aptamer Article de journal

Nat Chem Biol, 15 (5), p. 472-479, 2019, ISBN: 30992561.

Résumé | Liens | BibTeX | Étiquettes: RYCKELYNCK, Unité ARN

Ryckelynck, M

Development and engineering of artificial RNAs Article de journal

Methods, 161 , p. 1-2, 2019, ISBN: 31195094.

Liens | BibTeX | Étiquettes: RYCKELYNCK, Unité ARN

Autour, A; Bouhedda, F; Cubi, R; Ryckelynck, M

Optimization of fluorogenic RNA-based biosensors using droplet-based microfluidic ultrahigh-throughput screening Article de journal

Methods, 161 , p. 46-53, 2019, ISBN: 30902664.

Résumé | Liens | BibTeX | Étiquettes: RYCKELYNCK, RYCKELYNCK Aptasensors Fluorogenic biosensors High-throughput screening Light-up aptamer Next generation sequencing RNA, Unité ARN

2018

Trachman, 3rd R J; Abdolahzadeh, A; Andreoni, A; Cojocaru, R; Knutson, J R; Ryckelynck, M; Unrau, P J; Ferré-D'Amaré, A R

Crystal Structures of the Mango-II RNA Aptamer Reveal Heterogeneous Fluorophore Binding and Guide Engineering of Variants with Improved Selectivity and Brightness Article de journal

Biochemistry, 57 (26), p. 3544-3548, 2018, ISBN: 29768001.

Résumé | Liens | BibTeX | Étiquettes: RYCKELYNCK, Unité ARN

Bouhedda, F; Autour, A; Ryckelynck, M

Light-Up RNA Aptamers and Their Cognate Fluorogens: From Their Development to Their Applications Article de journal

Int J Mol Sci, 19 (1), p. 44, 2018, ISBN: 29295531.

Résumé | Liens | BibTeX | Étiquettes: RYCKELYNCK, RYCKELYNCK WESTHOF RNA biosensing fluorescence fluorogen fluorogenic dye gene expression monitoring in vitro evolution light-up aptamer live-cell imaging, Unité ARN

Autour, A; Jeng, S C Y; Cawte, A D; Abdolahzadeh, A; Galli, A; Panchapakesan, SSS.; Rueda, D; Ryckelynck, M; Unrau, P J

Fluorogenic RNA Mango aptamers for imaging small non-coding RNAs in mammalian cells Article de journal

Nat Commun, 9 (1), p. 656, 2018, ISBN: 29440634.

Résumé | Liens | BibTeX | Étiquettes: RYCKELYNCK, RYCKELYNCK WESTHOF, Unité ARN

2017

Fernandez-Millan, P; Autour, A; Ennifar, E; Westhof, E; Ryckelynck, M

Crystal structure and fluorescence properties of the iSpinach aptamer in complex with DFHBI Article de journal

RNA, 23 (12), p. 1788-1795, 2017, ISBN: 28939697.

Résumé | Liens | BibTeX | Étiquettes: ENNIFAR, ENNIFAR WESTHOF RYCKELYNCK DFHBI Spinach crystal structure fluorescence fluorogenic RNA aptamer, RYCKELYNCK, Unité ARN, WESTHOF

2016

Autour, A; Westhof, E; Ryckelynck, M

iSpinach: a fluorogenic RNA aptamer optimized for in vitro applications. Article de journal

Nucleic Acids Res, 44 (6), p. 2491-2500, 2016, ISBN: 26932363.

Résumé | Liens | BibTeX | Étiquettes: RYCKELYNCK, Unité ARN, WESTHOF

Matsumura, S; Kun, A; Ryckelynck, M; Coldren, F; Szilagyi, A; Jossinet, F; Rick, C; Nghe, P; Szathmary, E; Griffiths, A D

Transient compartmentalization of RNA replicators prevents extinction due to parasites. Article de journal

Science, 354 (6317), p. 1293-1296, 2016, ISBN: 27940874.

Résumé | Liens | BibTeX | Étiquettes: JOSSINET RYCKELYNCK WESTHOF, RYCKELYNCK, Unité ARN

2015

Woronoff, G; Ryckelynck, M; Wessel, J; Schicke, O; Griffiths, A; P., Soumillion

Activity-Fed Translation (AFT) Assay: A New High-Throughput Screening Strategy for Enzymes in Droplets. Article de journal

Chembiochem, 16 (9), p. 1343-1349, 2015.

Résumé | Liens | BibTeX | Étiquettes: RYCKELYNCK, Unité ARN, WESTHOF droplet-based microfluidics enzyme catalysis in vitro translation penicillin acylase protein expression

Ryckelynck, M; Baudrey, S; Rick, C; Marin, A; Coldren, F; Westhof, E; Griffiths, A D

Using droplet-based microfluidics to improve the catalytic properties of RNA under multiple-turnover conditions. Article de journal

RNA, 21 (3), p. 458-469, 2015, ISBN: 25605963.

Résumé | Liens | BibTeX | Étiquettes: RYCKELYNCK, Unité ARN, WESTHOF, WESTHOF RNA droplet-based microfluidics high-throughput screening in vitro evolution ribozymes

2008

Ryckelynck, M; Paulus, C A; Frugier, M

Post-Translational Modifications Guard Yeast from Misaspartylation Article de journal

Biochemistry, 47 (47), p. 12476-12482, 2008, ISBN: 18956891, (1520-4995 (Electronic) 0006-2960 (Linking) Journal article).

Résumé | Liens | BibTeX | Étiquettes: ERIANI, FRUGIER, RYCKELYNCK, Unité ARN

2005

Ryckelynck, M; Masquida, B; Giege, R; Frugier, M

An intricate RNA structure with two tRNA-derived motifs directs complex formation between yeast aspartyl-tRNA synthetase and its mRNA Article de journal

J Mol Biol, 354 (3), p. 614-629, 2005, ISBN: 16257416, (0022-2836 (Print) Journal Article).

Résumé | Liens | BibTeX | Étiquettes: ERIANI, FRUGIER, Messenger/*chemistry/*metabolism RNA, Molecular Molecular Sequence Data Nucleic Acid Conformation Protein Structure, Non-U.S. Gov't Saccharomyces cerevisiae/*enzymology/*genetics Sequence Alignment Sequence Homology, Nucleic Acid Solubility, RYCKELYNCK, Tertiary RNA, Transfer/*chemistry/*metabolism Research Support, Unité ARN, WESTHOF GIEGE FRUGIER Aspartate-tRNA Ligase/genetics/*metabolism Base Sequence DNA Footprinting Gene Deletion Models

Ryckelynck, M; Giege, R; Frugier, M

tRNAs and tRNA mimics as cornerstones of aminoacyl-tRNA synthetase regulations Article de journal

Biochimie, 87 (9-10), p. 835-845, 2005, ISBN: 15925436, (0300-9084 Journal article).

Résumé | Liens | BibTeX | Étiquettes: ERIANI, FRUGIER, GIEGE FRUGIER, RYCKELYNCK, Unité ARN

Frugier, M; Ryckelynck, M; Giege, R

tRNA-balanced expression of a eukaryal aminoacyl-tRNA synthetase by an mRNA-mediated pathway Article de journal

EMBO Rep, 6 (9), p. 860-865, 2005, ISBN: 16113655, (1469-221x Journal article).

Résumé | Liens | BibTeX | Étiquettes: ERIANI, FRUGIER, GIEGE FRUGIER, RYCKELYNCK, Unité ARN

2003

Ryckelynck, M; Giege, R; Frugier, M

Yeast tRNA(Asp) charging accuracy is threatened by the N-terminal extension of aspartyl-tRNA synthetase Article de journal

J Biol Chem, 278 (11), p. 9683-9690, 2003, ISBN: 12486031, (0021-9258 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Amino Acid Motifs Aspartate-tRNA Ligase/*metabolism Aspartic Acid/chemistry Base Sequence Codon Escherichia coli/metabolism Kinetics Molecular Sequence Data Nucleic Acid Conformation Nucleic Acids/chemistry Protein Structure, Asp/*chemistry Support, ERIANI, FRUGIER, Messenger/metabolism RNA, Non-U.S. Gov't Yeasts/metabolism, RYCKELYNCK, Secondary Protein Structure, Tertiary RNA, Transfer, Unité ARN