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2018

Issa, Najwa; Guillaumot, Nina; Lauret, Emilie; Matt, Nicolas; Scaeffer-Reiss, Christine; Dorsselaer, Alain Van; Reichhart, Jean-Marc; Veillard, Florian

The circulating protease Persephone is an immune sensor for microbial proteolytic activities upstream of the Drosophila Toll pathway. Article de journal

Molecular Cell, 69 (4), p. 539-550, 2018, ISSN: 1097-2765.

Résumé | Liens | BibTeX | Étiquettes: circulating protease, immune sensor, M3i, matt, persephone, Protease, proteolitic activities, reichhart, toll pathway

2017

Koltun, Bella; Shackelford, Eliza; Bonnay, François; Matt, Nicolas; Reichhart, Jean-Marc; Orian, Amir

The SUMO-targeted ubiquitin ligase, Dgrn, is essential for Drosophila innate immunity Article de journal

The International Journal of Developmental Biology, 61 (3-4-5), p. 319–327, 2017, ISSN: 0214-6282.

Liens | BibTeX | Étiquettes: Dgrn, Drosophila, innate immunity, Ligase, M3i, matt, reichhart, SUMO, target, ubiquitin

Chamy, Laure El; Matt, Nicolas; Reichhart, Jean-Marc

Advances in Myeloid-Like Cell Origins and Functions in the Model Organism Drosophila melanogaster Article de journal

Microbiology Spectrum, 5 (1), 2017, ISSN: 2165-0497.

Liens | BibTeX | Étiquettes: Drosophila melanogaster, M3i, matt, Myeloid-Like Cell Origins, reichhart

2016

Baron, Olga Lucia; Deleury, Emeline; Reichhart, Jean-Marc; Coustau, Christine

The LBP/BPI multigenic family in invertebrates: Evolutionary history and evidences of specialization in mollusks Article de journal

Developmental & Comparative Immunology, 57 , p. 20–30, 2016, ISSN: 0145305X.

Liens | BibTeX | Étiquettes: BPI, Evolution, Invertebrate, LBP, M3i, mollusks, multigenic family, reichhart

2015

Veillard, Florian; Troxler, Laurent; Reichhart, Jean-Marc

Drosophila melanogaster clip-domain serine proteases: Structure, function and regulation Article de journal

Biochimie, 122 , p. 255-269, 2015, ISBN: 0300-9084.

Résumé | Liens | BibTeX | Étiquettes: bioinformatic, Chymotrypsin, clip domain, Immunity, Insect, M3i, Melanization, reichhart, Serine Proteases, Serpin, Toll

Chamy, Laure El; Matt, Nicolas; Ntwasa, Monde; Reichhart, Jean-Marc

The multilayered innate immune defense of the gut Article de journal

Biomed J, 38 (4), p. 276–284, 2015, ISSN: 2320-2890.

Résumé | Liens | BibTeX | Étiquettes: fly, gut, innate immunity, M3i, matt, reichhart

2014

Bonnay, François; Nguyen, Xuan-Hung; Cohen-Berros, Eva; Troxler, Laurent; Batsche, Eric; Camonis, Jacques; Takeuchi, Osamu; Reichhart, Jean-Marc; Matt, Nicolas

Akirin specifies NF-κB selectivity of Drosophila innate immune response via chromatin remodeling Article de journal

EMBO J., 33 (20), p. 2349–2362, 2014, ISSN: 1460-2075.

Résumé | Liens | BibTeX | Étiquettes: Animals, bioinformatic, Cell Cycle Proteins, Chromatin Assembly and Disassembly, chromatin remodeling, DNA-Binding Proteins, Female, Genetic, Immunity, Innate, Innate immune response, M3i, Male, matt, Mutation, NF-kappa B, NF‐κB, Promoter Regions, proteomics, reichhart, Trans-Activators, Transcription Factors, Transcriptional Activation, Two-Hybrid System Techniques

Tartey, Sarang; Matsushita, Kazufumi; Vandenbon, Alexis; Ori, Daisuke; Imamura, Tomoko; Mino, Takashi; Standley, Daron M; Hoffmann, Jules A; Reichhart, Jean-Marc; Akira, Shizuo; Takeuchi, Osamu

Akirin2 is critical for inducing inflammatory genes by bridging IκB-ζ and the SWI/SNF complex Article de journal

EMBO J., 33 (20), p. 2332–2348, 2014, ISSN: 1460-2075.

Résumé | Liens | BibTeX | Étiquettes: Adaptor Proteins, Animals, Cell Nucleus, Chromatin Assembly and Disassembly, chromatin remodeling, Chromosomal Proteins, cytokine, Cytokines, Female, Gene Expression Regulation, gene regulation, Genetic, hoffmann, Humans, Immunity, Innate, innate immunity, Knockout, Listeria monocytogenes, M3i, Macrophages, Male, Mice, Multiprotein Complexes, Non-Histone, Nuclear Proteins, Promoter Regions, Protein Binding, reichhart, Repressor Proteins, Sequence Deletion, Signal Transducing, Transcriptional Activation

Leclerc, Vincent; Chamy, Laure El; Ntwasa, Monde; Reichhart, Jean-Marc

Drosophila melanogaster model in innate immunity. Article de journal

Trends in Entomology, 10 , p. 73–86, 2014.

Résumé | BibTeX | Étiquettes: M3i, reichhart

2013

Kobayashi, Taira; Ogawa, Michinaga; Sanada, Takahito; Mimuro, Hitomi; Kim, Minsoo; Ashida, Hiroshi; Akakura, Reiko; Yoshida, Mitsutaka; Kawalec, Magdalena; Reichhart, Jean-Marc; Mizushima, Tsunehiro; Sasakawa, Chihiro

The Shigella OspC3 effector inhibits caspase-4, antagonizes inflammatory cell death, and promotes epithelial infection Article de journal

Cell Host Microbe, 13 (5), p. 570–583, 2013, ISSN: 1934-6069.

Résumé | Liens | BibTeX | Étiquettes: Animal, Animals, Bacillary, Bacterial, Bacterial Proteins, Caspases, Cell Death, Cell Line, Disease Models, DNA, Dysentery, Enzyme Inhibitors, Epithelial Cells, Escherichia coli, Gene Knockout Techniques, Guinea Pigs, Host-Pathogen Interactions, Humans, Initiator, M3i, Protein Binding, Protein Interaction Mapping, reichhart, Salmonella typhimurium, Sequence Analysis, Shigella flexneri, Virulence Factors

Bonnay, François; Cohen-Berros, Eva; Hoffmann, Martine; Kim, Sabrina Y; Boulianne, Gabrielle L; Hoffmann, Jules A; Matt, Nicolas; Reichhart, Jean-Marc

Big bang gene modulates gut immune tolerance in Drosophila Article de journal

Proc. Natl. Acad. Sci. U.S.A., 110 (8), p. 2957–2962, 2013, ISSN: 1091-6490.

Résumé | Liens | BibTeX | Étiquettes: Animals, hoffmann, Immune Tolerance, Longevity, M3i, matt, Membrane Proteins, reichhart

Baron, Olga Lucia; van West, Pieter; Industri, Benoit; Ponchet, Michel; Dubreuil, Géraldine; Gourbal, Benjamin; Reichhart, Jean-Marc; Coustau, Christine

Parental transfer of the antimicrobial protein LBP/BPI protects Biomphalaria glabrata eggs against oomycete infections Article de journal

PLoS Pathog., 9 (12), p. e1003792, 2013, ISSN: 1553-7374.

Résumé | Liens | BibTeX | Étiquettes: Acute-Phase Proteins, Animals, Antimicrobial Cationic Peptides, Biomphalaria, Blood Proteins, Carrier Proteins, Cell Membrane, Cell Membrane Permeability, Cloning, Escherichia coli, Female, Immunity, infection, M3i, Maternally-Acquired, Membrane Glycoproteins, Microbial Sensitivity Tests, Molecular, Oomycetes, Recombinant Proteins, reichhart, Zygote

2012

Ezekowitz, Alan R B; Dimarcq, Jean-Luc; Kafatos, Fotis; Levashina, Elena A; Ferrandon, Dominique; Hetru, Charles; Imler, Jean-Luc; Reichhart, Jean-Marc

Lawrence's book review unfair to Hoffmann Article de journal

Curr. Biol., 22 (12), p. R482, 2012, ISSN: 1879-0445.

Liens | BibTeX | Étiquettes: Book Reviews as Topic, Ethics, ferrandon, imler, M3i, Professional, reichhart

Lemaitre, Bruno; Nicolas, Emmanuelle; Michaut, Lydia; Reichhart, Jean-Marc; Hoffmann, Jules A

Pillars article: the dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell. 1996. 86: 973-983 Article de journal

J. Immunol., 188 (11), p. 5210–5220, 2012, ISSN: 1550-6606.

Résumé | BibTeX | Étiquettes: Animals, Antifungal Agents, Developmental, DNA-Binding Proteins, Gene Expression Regulation, history, hoffmann, M3i, Multigene Family, Mycoses, Phosphoproteins, reichhart, Toll-Like Receptors

Deleury, Emeline; Dubreuil, Géraldine; Elangovan, Namasivayam; Wajnberg, Eric; Reichhart, Jean-Marc; Gourbal, Benjamin; Duval, David; Baron, Olga Lucia; Gouzy, Jérôme; Coustau, Christine

Specific versus non-specific immune responses in an invertebrate species evidenced by a comparative de novo sequencing study Article de journal

PLoS ONE, 7 (3), p. e32512, 2012, ISSN: 1932-6203.

Résumé | Liens | BibTeX | Étiquettes: Animals, Biomphalaria, Calmodulin, Cluster Analysis, Complementary, DNA, Expressed Sequence Tags, Ferritins, Gene Expression Profiling, Gene Expression Regulation, High-Throughput Nucleotide Sequencing, Immunity, Innate, M3i, messenger, Pattern Recognition, Phylogeny, Receptors, reichhart, RNA, Signal Transduction, Zinc Fingers

2011

Boyer, Laurent; Magoc, Lorin; Dejardin, Stephanie; Cappillino, Michael; Paquette, Nicholas; Hinault, Charlotte; Charriere, Guillaume M; Ip, Eddie W K; Fracchia, Shannon; Hennessy, Elizabeth; Erturk-Hasdemir, Deniz; Reichhart, Jean-Marc; Silverman, Neal; Lacy-Hulbert, Adam; Stuart, Lynda M

Pathogen-derived effectors trigger protective immunity via activation of the Rac2 enzyme and the IMD or Rip kinase signaling pathway Article de journal

Immunity, 35 (4), p. 536–549, 2011, ISSN: 1097-4180.

Résumé | Liens | BibTeX | Étiquettes: Adaptor Proteins, Enzyme Activation, HEK293 Cells, Humans, M3i, rac GTP-Binding Proteins, Receptor-Interacting Protein Serine-Threonine Kinases, reichhart, Signal Transducing, Signal Transduction

Ogawa, Michinaga; Yoshikawa, Yuko; Kobayashi, Taira; Mimuro, Hitomi; Fukumatsu, Makoto; Kiga, Kotaro; Piao, Zhenzi; Ashida, Hiroshi; Yoshida, Mitsutaka; Kakuta, Shigeru; Koyama, Tomohiro; Goto, Yoshiyuki; Nagatake, Takahiro; Nagai, Shinya; Kiyono, Hiroshi; Kawalec, Magdalena; Reichhart, Jean-Marc; Sasakawa, Chihiro

A Tecpr1-dependent selective autophagy pathway targets bacterial pathogens Article de journal

Cell Host Microbe, 9 (5), p. 376–389, 2011, ISSN: 1934-6069.

Résumé | Liens | BibTeX | Étiquettes: Animals, Autophagy, Biological, Cells, Cultured, M3i, Membrane Proteins, Mice, Microtubule-Associated Proteins, Models, Phagosomes, Protein Interaction Mapping, reichhart, Shigella, Two-Hybrid System Techniques

Kellenberger, Christine; Leone, Philippe; Coquet, Laurent; Jouenne, Thierry; Reichhart, Jean-Marc; Roussel, Alain

Structure-function analysis of grass clip serine protease involved in Drosophila Toll pathway activation Article de journal

J. Biol. Chem., 286 (14), p. 12300–12307, 2011, ISSN: 1083-351X.

Résumé | Liens | BibTeX | Étiquettes: Animals, Catalytic Domain, Cell Line, M3i, reichhart, Serine Proteases, Signal Transduction, Structure-Activity Relationship, Toll-Like Receptors

Reichhart, Jean-Marc; Gubb, David; Leclerc, Vincent

The Drosophila serpins: multiple functions in immunity and morphogenesis Article de journal

Meth. Enzymol., 499 , p. 205–225, 2011, ISSN: 1557-7988.

Résumé | Liens | BibTeX | Étiquettes: Animals, Immunity, Innate, M3i, Morphogenesis, reichhart, Serpins, Signal Transduction

2010

Silverman, Gary A; Whisstock, James C; Bottomley, Stephen P; Huntington, James A; Kaiserman, Dion; Luke, Cliff J; Pak, Stephen C; Reichhart, Jean-Marc; Bird, Phillip I

Serpins flex their muscle: I. Putting the clamps on proteolysis in diverse biological systems Article de journal

J. Biol. Chem., 285 (32), p. 24299–24305, 2010, ISSN: 1083-351X.

Résumé | Liens | BibTeX | Étiquettes: Animals, Biological, Caenorhabditis elegans, Cell Death, Cell Differentiation, Cell Survival, Homeostasis, Humans, Immunity, Innate, M3i, Mice, Models, Phenotype, reichhart, Serpins, Transgenes, transgenic

Whisstock, James C; Silverman, Gary A; Bird, Phillip I; Bottomley, Stephen P; Kaiserman, Dion; Luke, Cliff J; Pak, Stephen C; Reichhart, Jean-Marc; Huntington, James A

Serpins flex their muscle: II. Structural insights into target peptidase recognition, polymerization, and transport functions Article de journal

J. Biol. Chem., 285 (32), p. 24307–24312, 2010, ISSN: 1083-351X.

Résumé | Liens | BibTeX | Étiquettes: Animals, Biological, Biological Transport, Biophysics, Catalytic Domain, Hormones, Humans, Kinetics, M3i, Models, Peptide Hydrolases, Protein Binding, Protein Conformation, Protein Structure, reichhart, Serpins, Substrate Specificity, Tertiary, Thrombin

Garcia, Alvaro Baeza; Pierce, Raymond J; Gourbal, Benjamin; Werkmeister, Elisabeth; Colinet, Dominique; Reichhart, Jean-Marc; Dissous, Colette; Coustau, Christine

Involvement of the cytokine MIF in the snail host immune response to the parasite Schistosoma mansoni Article de journal

PLoS Pathog., 6 (9), p. e1001115, 2010, ISSN: 1553-7374.

Résumé | Liens | BibTeX | Étiquettes: Amino Acid, Animals, Apoptosis, Biomphalaria, Blotting, Cell Proliferation, Cells, Cricetinae, Cultured, Hemocytes, Host-Parasite Interactions, Humans, Liver, M3i, Macrophage Migration-Inhibitory Factors, messenger, Oocysts, Recombinant Proteins, reichhart, Reverse Transcriptase Polymerase Chain Reaction, RNA, Schistosoma mansoni, Schistosomiasis mansoni, Sequence Homology, Small Interfering, Western

Paquette, Nicholas; Broemer, Meike; Aggarwal, Kamna; Chen, Li; Husson, Marie; Ertürk-Hasdemir, Deniz; Reichhart, Jean-Marc; Meier, Pascal; Silverman, Neal

Caspase-mediated cleavage, IAP binding, and ubiquitination: linking three mechanisms crucial for Drosophila NF-kappaB signaling Article de journal

Mol. Cell, 37 (2), p. 172–182, 2010, ISSN: 1097-4164.

Résumé | Liens | BibTeX | Étiquettes: Alleles, Amino Acid Motifs, Animals, Biological, Caspases, Inhibitor of Apoptosis Proteins, M3i, MAP Kinase Kinase Kinases, Models, NF-kappa B, reichhart, Sequence Alignment, Signal Transduction, Ubiquitin-Protein Ligases, Ubiquitination

2009

Shia, Alice K H; Glittenberg, Marcus; Thompson, Gavin; Weber, Alexander N R; Reichhart, Jean-Marc; Ligoxygakis, Petros

Toll-dependent antimicrobial responses in Drosophila larval fat body require Spätzle secreted by haemocytes Article de journal

J. Cell. Sci., 122 (Pt 24), p. 4505–4515, 2009, ISSN: 1477-9137.

Résumé | Liens | BibTeX | Étiquettes: Animals, Enterococcus faecalis, Escherichia coli, Fat Body, Hemocytes, Larva, M3i, reichhart, Toll-Like Receptors

Leclerc, Vincent; Caldelari, Isabelle; Veresceaghina, N; Reichhart, Jean-Marc

Phagocytosis in Drosophila melanogaster Immune Response. incollection

Phagocyte-pathogen Interactions, 33 , p. 513–521, DG Russel and S. Gordon, Whasington, DC, 2009.

BibTeX | Étiquettes: M3i, reichhart

2008

Chamy, Laure El; Leclerc, Vincent; Caldelari, Isabelle; Reichhart, Jean-Marc

Sensing of 'danger signals' and pathogen-associated molecular patterns defines binary signaling pathways 'upstream' of Toll Article de journal

Nat. Immunol., 9 (10), p. 1165–1170, 2008, ISSN: 1529-2916.

Résumé | Liens | BibTeX | Étiquettes: Animals, Fungi, Genetically Modified, Gram-Positive Bacteria, Gram-Positive Bacterial Infections, In Situ Hybridization, M3i, Mycoses, Pattern Recognition, Peptide Hydrolases, Receptors, reichhart, Serine Endopeptidases, Signal Transduction, Toll-Like Receptors

Goto, Akira; Matsushita, Kazufumi; Gesellchen, Viola; Chamy, Laure El; Kuttenkeuler, David; Takeuchi, Osamu; Hoffmann, Jules A; Akira, Shizuo; Boutros, Michael; Reichhart, Jean-Marc

Akirins are highly conserved nuclear proteins required for NF-kappaB-dependent gene expression in drosophila and mice Article de journal

Nat. Immunol., 9 (1), p. 97–104, 2008, ISSN: 1529-2916.

Résumé | Liens | BibTeX | Étiquettes: Animals, Cell Line, Embryo, Fibroblasts, hoffmann, Humans, Immunity, Innate, Interleukin-1beta, M3i, Mammalian, Mice, NF-kappa B, Nuclear Proteins, Proteins, reichhart, Signal Transduction, Toll-Like Receptors, transgenic, Tumor Necrosis Factor-alpha

2007

Gubb, David; Robertson, Andrew S; Troxler, Laurent; Reichhart, Jean-Marc

Drosophila Serpins: Regulatory Cascades in Innate Immunity and Morphogenesis incollection

Molecular and Cellular Aspects of the Serpinopathies and Disorders in Serpin Activity, p. 207–227, Silverman GA and Lomas DA, London UK, 2007.

BibTeX | Étiquettes: bioinformatic, innate immunity, M3i, Morphogenesis, regulatory Cascades, reichhart, Serpins

2006

Gottar, Marie; Gobert, Vanessa; Matskevich, Alexey A; Reichhart, Jean-Marc; Wang, Chengshu; Butt, Tariq M; Belvin, Marcia; Hoffmann, Jules A; Ferrandon, Dominique

Dual detection of fungal infections in Drosophila via recognition of glucans and sensing of virulence factors Article de journal

Cell, 127 (7), p. 1425–1437, 2006, ISSN: 0092-8674.

Résumé | Liens | BibTeX | Étiquettes: Animals, Antibody Formation, Beauveria, Candida albicans, Carrier Proteins, Cellular, ferrandon, Glucans, hoffmann, Immunity, Immunological, M3i, Metarhizium, Models, Polysaccharides, reichhart, Serine Endopeptidases, Signal Transduction, Virulence Factors

Leclerc, Vincent; Pelte, Nadège; Chamy, Laure El; Martinelli, Cosimo; Ligoxygakis, Petros; Hoffmann, Jules A; Reichhart, Jean-Marc

Prophenoloxidase activation is not required for survival to microbial infections in Drosophila Article de journal

EMBO Rep., 7 (2), p. 231–235, 2006, ISSN: 1469-221X.

Résumé | Liens | BibTeX | Étiquettes: Animals, Bacterial Infections, Catechol Oxidase, Enzyme Activation, Enzyme Precursors, Gram-Negative Bacteria, Gram-Positive Bacteria, Hemolymph, hoffmann, Immunity, Innate, M3i, Mutation, reichhart, Survival Rate

Pelte, Nadège; Robertson, Andrew S; Zou, Zhen; Belorgey, Didier; Dafforn, Timothy R; Jiang, Haobo; Lomas, David; Reichhart, Jean-Marc; Gubb, David

Immune challenge induces N-terminal cleavage of the Drosophila serpin Necrotic Article de journal

Insect Biochem. Mol. Biol., 36 (1), p. 37–46, 2006, ISSN: 0965-1748.

Résumé | Liens | BibTeX | Étiquettes: Animals, Gene Expression Regulation, M3i, Protein Conformation, reichhart, Serpins, Signal Transduction

2005

Reichhart, Jean-Marc

Tip of another iceberg: Drosophila serpins Article de journal

Trends Cell Biol., 15 (12), p. 659–665, 2005, ISSN: 0962-8924.

Résumé | Liens | BibTeX | Étiquettes: Animals, Immunity, M3i, Protein Conformation, reichhart, Serine Proteinase Inhibitors, Serpins

Kocks, Christine; Cho, Ju Hyun; Nehme, Nadine; Ulvila, Johanna; Pearson, Alan M; Meister, Marie; Strom, Charles; Conto, Stephanie L; Hetru, Charles; Stuart, Lynda M; Stehle, Thilo; Hoffmann, Jules A; Reichhart, Jean-Marc; Ferrandon, Dominique; Rämet, Mika; Ezekowitz, Alan R B

Eater, a transmembrane protein mediating phagocytosis of bacterial pathogens in Drosophila Article de journal

Cell, 123 (2), p. 335–346, 2005, ISSN: 0092-8674.

Résumé | Liens | BibTeX | Étiquettes: Amino Acid, Amino Acid Motifs, Animals, Bacterial Infections, Cell Surface, Embryo, Escherichia coli, ferrandon, Flow Cytometry, Frameshift Mutation, Genes, Histidine, hoffmann, In Situ Hybridization, Insect, Insect Proteins, M3i, Macrophages, Membrane Proteins, messenger, Nonmammalian, Open Reading Frames, Phagocytosis, Receptors, reichhart, RNA, RNA Interference, Sequence Homology, Serratia marcescens

Royet, Julien; Reichhart, Jean-Marc; Hoffmann, Jules A

Sensing and signaling during infection in Drosophila Article de journal

Curr. Opin. Immunol., 17 (1), p. 11–17, 2005, ISSN: 0952-7915.

Résumé | Liens | BibTeX | Étiquettes: Animals, Antimicrobial Cationic Peptides, Bacterial Infections, Gene Expression Regulation, Genome, hoffmann, Immunity, Innate, M3i, reichhart, Signal Transduction

Martinelli, Cosimo; Reichhart, Jean-Marc

Evolution and integration of innate immune systems from fruit flies to man: lessons and questions Article de journal

J. Endotoxin Res., 11 (4), p. 243–248, 2005, ISSN: 0968-0519.

Résumé | Liens | BibTeX | Étiquettes: Animals, Biological Evolution, Cell Surface, Forecasting, Humans, Immunity, Immunological, Innate, M3i, Membrane Glycoproteins, Models, Receptors, reichhart, Signal Transduction, Toll-Like Receptor 5, Toll-Like Receptors

2004

Leclerc, Vincent; Reichhart, Jean-Marc

The immune response of Drosophila melanogaster Article de journal

Immunol. Rev., 198 , p. 59–71, 2004, ISSN: 0105-2896.

Résumé | BibTeX | Étiquettes: Animals, Cell Surface, Immunity, Immunological, Innate, M3i, Models, Receptors, reichhart, Signal Transduction, Toll-Like Receptors

Montagnani, C; Kappler, Christine; Reichhart, Jean-Marc; Escoubas, J M

Cg-Rel, the first Rel/NF-kappaB homolog characterized in a mollusk, the Pacific oyster Crassostrea gigas. Article de journal

FEBS Lett., 561 , p. 75–82, 2004.

Résumé | BibTeX | Étiquettes: M3i, reichhart

Reichhart, Jean-Marc

Guest Editor of the Special Issue on Innate Immunity. Article de journal

Mol. Immunol., 40 , p. 843, 2004.

BibTeX | Étiquettes: M3i, reichhart

Imler, Jean-Luc; Ferrandon, Dominique; Royet, Julien; Reichhart, Jean-Marc; Hetru, Charles; Hoffmann, Jules A

Toll-dependent and Toll-independent immune responses in Drosophila Article de journal

Journal of Endotoxin Research, 10 (4), p. 241–246, 2004, ISSN: 0968-0519.

Résumé | Liens | BibTeX | Étiquettes: Acute-Phase Proteins, Animals, Blood Proteins, Cell Surface, ferrandon, hoffmann, imler, Insect Proteins, M3i, Membrane Glycoproteins, Receptors, reichhart, Toll-Like Receptor 5, Toll-Like Receptors, Up-Regulation

2003

Ligoxygakis, Petros; Roth, Siegfried; Reichhart, Jean-Marc

A serpin regulates dorsal-ventral axis formation in the Drosophila embryo Article de journal

Curr. Biol., 13 (23), p. 2097–2102, 2003, ISSN: 0960-9822.

Résumé | BibTeX | Étiquettes: Animals, Body Patterning, Cell Surface, Crosses, Female, Genetic, Immunohistochemistry, M3i, Microinjections, Receptors, reichhart, Serine Proteinase Inhibitors, Serpins, Signal Transduction, Toll-Like Receptors

Reichhart, Jean-Marc

TLR5 takes aim at bacterial propeller Article de journal

Nat. Immunol., 4 (12), p. 1159–1160, 2003, ISSN: 1529-2908.

Liens | BibTeX | Étiquettes: Animals, Bacterial Physiological Phenomena, Cell Surface, Flagella, Flagellin, Humans, M3i, Membrane Glycoproteins, Receptors, reichhart, Toll-Like Receptor 5, Toll-Like Receptors

Royet, Julien; Reichhart, Jean-Marc

Detection of peptidoglycans by NOD proteins Article de journal

Trends Cell Biol., 13 (12), p. 610–614, 2003, ISSN: 0962-8924.

Résumé | BibTeX | Étiquettes: Adaptor Proteins, Apoptosis, Carrier Proteins, Gram-Positive Bacteria, Humans, Immunity, Immunologic, Innate, M3i, Nod1 Signaling Adaptor Protein, Oligopeptides, peptidoglycan, Receptors, reichhart, Signal Transducing, Signal Transduction

Goto, Akira; Blandin, Stéphanie A; Royet, Julien; Reichhart, Jean-Marc; Levashina, Elena A

Silencing of Toll pathway components by direct injection of double-stranded RNA into Drosophila adult flies Article de journal

Nucleic Acids Res., 31 (22), p. 6619–6623, 2003, ISSN: 1362-4962.

Résumé | BibTeX | Étiquettes: Animals, blandin, Cell Surface, Double-Stranded, Epistasis, Female, Genetic, Green Fluorescent Proteins, Homeodomain Proteins, Luminescent Proteins, M3i, Phenotype, Receptors, reichhart, RNA, RNA Interference, Serpins, Signal Transduction, Time Factors, Toll-Like Receptors, Transcription Factors

Green, Clare; Brown, Gemma; Dafforn, Timothy R; Reichhart, Jean-Marc; Morley, Terri; Lomas, David A; Gubb, David

Drosophila necrotic mutations mirror disease-associated variants of human serpins Article de journal

Development, 130 (7), p. 1473–1478, 2003, ISSN: 0950-1991.

Résumé | BibTeX | Étiquettes: Animals, Humans, M3i, Necrosis, reichhart, Serpins, Temperature, Urea

2002

Ligoxygakis, Petros; Pelte, Nadège; Ji, Chuanyi; Leclerc, Vincent; Duvic, Bernard; Belvin, Marcia; Jiang, Haobo; Hoffmann, Jules A; Reichhart, Jean-Marc

A serpin mutant links Toll activation to melanization in the host defence of Drosophila Article de journal

EMBO J., 21 (23), p. 6330–6337, 2002, ISSN: 0261-4189.

Résumé | BibTeX | Étiquettes: Animals, Cell Surface, Hemolymph, hoffmann, infection, M3i, Melanins, Receptors, reichhart, Serpins, Toll-Like Receptors

Naitza, Silvia; Rossé, Carine; Kappler, Christine; Georgel, Philippe; Belvin, Marcia; Gubb, David; Camonis, Jacques; Hoffmann, Jules A; Reichhart, Jean-Marc

The Drosophila immune defense against gram-negative infection requires the death protein dFADD Article de journal

Immunity, 17 (5), p. 575–581, 2002, ISSN: 1074-7613.

Résumé | BibTeX | Étiquettes: Adaptor Proteins, Animals, Carrier Proteins, Fas-Associated Death Domain Protein, Gene Expression Regulation, Gram-Negative Bacterial Infections, hoffmann, Immunity, M3i, reichhart, Signal Transducing, Signal Transduction

Christophides, George K; Zdobnov, Evgeny; Barillas-Mury, Carolina; Birney, Ewan; Blandin, Stephanie A; Blass, Claudia; Brey, Paul T; Collins, Frank H; Danielli, Alberto; Dimopoulos, George; Hetru, Charles; Hoa, Ngo T; Hoffmann, Jules A; Kanzok, Stefan M; Letunic, Ivica; Levashina, Elena A; Loukeris, Thanasis G; Lycett, Gareth; Meister, Stephan; Michel, Kristin; Moita, Luis F; Müller, Hans-Michael; Osta, Mike A; Paskewitz, Susan M; Reichhart, Jean-Marc; Rzhetsky, Andrey; Troxler, Laurent; Vernick, Kenneth D; Vlachou, Dina; Volz, Jennifer; von Mering, Christian; Xu, Jiannong; Zheng, Liangbiao; Bork, Peer; Kafatos, Fotis C

Immunity-related genes and gene families in Anopheles gambiae Article de journal

Science, 298 (5591), p. 159–165, 2002, ISSN: 1095-9203.

Résumé | Liens | BibTeX | Étiquettes: Alternative Splicing, Animals, Anopheles, Apoptosis, bacteria, bioinformatic, blandin, Catechol Oxidase, Computational Biology, Enzyme Precursors, Gene Expression Regulation, Genes, Genetic, Genome, hoffmann, Immunity, Innate, Insect, Insect Proteins, M3i, Multigene Family, Peptides, Phylogeny, Plasmodium, Protein Structure, reichhart, Selection, Serine Endopeptidases, Serpins, Signal Transduction, Tertiary

Ligoxygakis, Petros; Pelte, Nadège; Hoffmann, Jules A; Reichhart, Jean-Marc

Activation of Drosophila Toll during fungal infection by a blood serine protease Article de journal

Science, 297 (5578), p. 114–116, 2002, ISSN: 1095-9203.

Résumé | Liens | BibTeX | Étiquettes: Animals, Cell Surface, Chromosome Mapping, Escherichia coli, Female, Gene Expression Regulation, Genes, Gram-Positive Cocci, Hemolymph, hoffmann, Hypocreales, Insect, Insect Proteins, M3i, Male, Mutation, Protein Sorting Signals, Protein Structure, Receptors, reichhart, Serine Endopeptidases, Tertiary, Toll-Like Receptors

Hoffmann, Jules A; Reichhart, Jean-Marc

Drosophila innate immunity: an evolutionary perspective Article de journal

Nat. Immunol., 3 (2), p. 121–126, 2002, ISSN: 1529-2908.

Résumé | Liens | BibTeX | Étiquettes: Animals, Biological Evolution, Cell Surface, hoffmann, Immunity, Immunological, Innate, M3i, Membrane Glycoproteins, Models, Receptors, reichhart, Signal Transduction, Toll-Like Receptors

Ligoxygakis, Petros; Bulet, Philippe; Reichhart, Jean-Marc

Critical evaluation of the role of the Toll-like receptor 18-Wheeler in the host defense of Drosophila Article de journal

EMBO Rep., 3 (7), p. 666–673, 2002, ISSN: 1469-221X.

Résumé | Liens | BibTeX | Étiquettes: Animals, Anti-Bacterial Agents, Antimicrobial Cationic Peptides, Cell Adhesion Molecules, Fat Body, Gene Expression Regulation, Genes, Immunohistochemistry, Immunologic, Insect, Insect Proteins, Larva, M3i, Mass, Matrix-Assisted Laser Desorption-Ionization, Membrane Proteins, Receptors, reichhart, Reporter, Spectrometry, Transgenes

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