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2017

Volohonsky, Gloria; Hopp, Ann-Katrin; Saenger, Mélanie; Soichot, Julien; Scholze, Heidi; Boch, Jens; Blandin, Stéphanie A; Marois, Eric

Transgenic Expression of the Anti-parasitic Factor TEP1 in the Malaria Mosquito Anopheles gambiae Article de journal

PLOS Pathogens, 13 (1), p. e1006113, 2017, ISSN: 1553-7374.

Liens | BibTeX | Étiquettes: Anopheles gambiae, anti-parasitic factor, blandin, M3i, Malaria, marois, TEP1, transgenic

2016

Ehrhardt, Katharina; Deregnaucourt, Christiane; Goetz, Alice-Anne; Tzanova, Tzvetomira; Gallo, Valentina; Arese, Paolo; Pradines, Bruno; Adjalley, Sophie H; Bagrel, Denyse; Blandin, Stephanie A; Lanzer, Michael; Davioud-Charvet, Elisabeth

The redox-cycler plasmodione is a fast acting antimalarial lead compound with pronounced activity against sexual and early asexual blood-stage parasites Article de journal

Antimicrob. Agents Chemother., 60 (9), p. 5146-5158, 2016, ISSN: 1098-6596.

Résumé | Liens | BibTeX | Étiquettes: antimalarial, blandin, M3i, parasites, Plasmodium, redox-cycler

2015

Volohonsky, Gloria; Terenzi, Olivier; Soichot, Julien; Naujoks, Daniel A; Nolan, Tony; Windbichler, Nikolai; Kapps, Delphine; Smidler, Andie L; Vittu, Anaïs; Costa, Giulia; Steinert, Stefanie; Levashina, Elena A; Blandin, Stéphanie A; Marois, Eric

Tools for Anopheles gambiae Transgenesis Article de journal

G3 (Bethesda), 5 (6), p. 1151-63, 2015.

Résumé | Liens | BibTeX | Étiquettes: Anopheles gambiae, bioinformatic, blandin, M3i, marois, transgenesis

Neafsey, D E; Waterhouse, R M; Abai, M R; Aganezov, S S; Alekseyev, M A; Allen, J E; Amon, J; Arcà, B; Arensburger, P; Artemov, G; Assour, L A; Basseri, H; Berlin, A; Birren, B W; Blandin, Stéphanie A; Brockman, A I; Burkot, T R; Burt, A; Chan, C S; Chauve, C; Chiu, J C; Christensen, M; Costantini, C; Davidson, V L M; Deligianni, E; Dottorini, T; Dritsou, V; Gabriel, S B; Guelbeogo, W M; Hall, A B; Han, M W; Hlaing, T; Hughes, D S T; Jenkins, A M; Jiang, X; Jungreis, I; Kakani, E G; Kamali, M; Kemppainen, P; Kennedy, R C; Kirmitzoglou, I K; Koekemoer, L L; Laban, N; Langridge, N; Lawniczak, M K N; Lirakis, M; Lobo, N F; Lowy, E; MacCallum, R M; Mao, C; Maslen, G; Mbogo, C; McCarthy, J; Michel, K; Mitchell, S N; Moore, W; Murphy, K A; Naumenko, A N; Nolan, Tony; Novoa, E M; O’Loughlin, S; Oringanje, C; Oshaghi, M A; Pakpour, N; Papathanos, P A; Peery, A N; Povelones, Michael; Prakash, A; Price, D A; Rajaraman, A; Reimer, L J; Rinker, D C; Rokas, A; Russell, T L; Sagnon, N F; Sharakhova, M V; Shea, T; Simão, F A; Simard, F; Slotman, M A; Somboon, P; Stegniy, V; Struchiner, C J; Thomas, G W C; Tojo, M; Topalis, P; Tubio, J M C; Unger, M F; Vontas, J; Walton, C; Wilding, C S; Willis, J H; Wu, Y-C; Yan, G; Zdobnov, E M; Zhou, X; Catteruccia, Flaminia; Christophides, Georges K; Collins, F H; Cornman, R S; Crisanti, Andrea; Donnelly, M J; Emrich, S J; Fontaine, M C; Gelbart, W; Hahn, M W; Hansen, I A; Howell, P I; Kafatos, Fotis C; Kellis, M; Lawson, D; Louis, C; Luckhart, S; Muskavitch, M A T; Ribeiro, J M; Riehle, M A; Sharakhov, I V; Tu, Z; Zwiebel, L J; Besansky, N J

Highly evolvable malaria vectors: The genomes of 16 Anopheles mosquitoes. Article de journal

Science, 347 (6217), p. 1258522, 2015.

Résumé | Liens | BibTeX | Étiquettes: Anopheles, blandin, genomes, M3i

2013

Lamacchia, Marina; Clayton, John Randy; Wang-Sattler, R; Steinmetz, Lars M; Levashina, Elena A; Blandin, Stéphanie A

Silencing of Genes and Alleles by RNAi in Anopheles gambiae Article de journal

Methods Mol Biol., 923 , p. 161-76, 2013.

Résumé | BibTeX | Étiquettes: blandin, dsRNA, M3i, RNAi

2009

Blandin, Stéphanie A; Wang-Sattler, R; Lamacchia, Marina; Gagneur, Julien; Lycett, G; Ning, Y; Levashina, Elena A; Steinmetz, Lars M

Dissecting the genetic basis of resistance to malaria parasites in Anopheles gambiae Article de journal

Science, 326 (5949), p. 147-50, 2009.

Résumé | Liens | BibTeX | Étiquettes: blandin, M3i, TEP1

Fraiture, Malou; Baxter, Richard H G; Steinert, Stefanie; Chelliah, Yogarany; Frolet, Cécile; Quispe-Tintaya, Wilber; Hoffmann, Jules A; Blandin, Stéphanie A; Levashina, Elena A

Two mosquito LRR proteins function as complement control factors in the TEP1-mediated killing of Plasmodium Article de journal

Cell Host Microbe, 5 (3), p. 273–284, 2009, ISSN: 1934-6069.

Résumé | Liens | BibTeX | Étiquettes: Animals, Anopheles, APL1, Biological, blandin, Complement System Proteins, Hemolymph, hoffmann, Immunologic Factors, LRIM1, M3i, Models, Plasmodium, Protein Binding, Proteins, TEP1

2008

Blandin, Stéphanie A; Marois, Eric; Levashina, Elena A

Antimalarial responses in Anopheles gambiae: from a complement-like protein to a complement-like pathway Article de journal

Cell Host Microbe., 3 (6), p. 364-74, 2008.

Résumé | Liens | BibTeX | Étiquettes: blandin, M3i, marois, TEP1

Blandin, Stéphanie A; Levashina, Elena A

Reverse Genetics Analysis of Antiparasitic Responses in the Malaria Vector, Anopheles gambiae Article de journal

Methods Mol Biol., 415 , p. 365-77, 2008.

Résumé | Liens | BibTeX | Étiquettes: blandin, M3i, RNAi

2007

Blandin, Stéphanie A; Levashina, Elena A

Phagocytosis in mosquito immune responses Article de journal

Immunol Rev., 219 , p. 8-16, 2007.

Résumé | Liens | BibTeX | Étiquettes: blandin, M3i, Phagocytosis, RNAi

Baxter, Richard H; Chang, C I; Chelliah, Y; Blandin, Stéphanie A; Levashina, Elena A; Deisenhofer, J

Structural basis for conserved complement factor-like function in the antimalarial protein TEP1 Article de journal

Proc Natl Acad Sci U S A., 104 (28), p. 11615-20, 2007.

Résumé | Liens | BibTeX | Étiquettes: blandin, M3i, TEP1

Waterhouse, R M; Kriventseva, E V; Meister, Stephan; Xi, Z; Alvarez, K S; Bartholomay, L C; Barillas-Mury, Carolina; Bian, G; Blandin, Stéphanie A; Christensen, B M; Dong, Y; Jiang, H; Kanost, M R; Koutsos, A C; Levashina, Elena A; Li, J; Ligoxygakis, Petros; Maccallum, R M; Mayhew, G F; Mendes, A; Michel, K; Osta, M A; Paskewitz, S; Shin, S W; Vlachou, D; Wang, L; Wei, W; Zheng, L; Zou, Z; Severson, D W; Raikhel, A S; Kafatos, Fotis C; Dimopoulos, G; Zdobnov, E M; Christophides, G K

Evolutionary dynamics of immune-related genes and pathways in disease-vector mosquitoes Article de journal

Science, 316 , p. 5832, 2007.

Résumé | Liens | BibTeX | Étiquettes: blandin, Evolution, M3i, Phylogeny

Lefevre, T; Thomas, F; Schwartz, A; Levashina, Elena A; Blandin, Stéphanie A; Brizard, J-P; Bourligu, Le L; Demettre, E; Renaud, F; Biron, D G

Malaria Plasmodium agent induces alteration in the head proteome of their Anopheles mosquito host Article de journal

Proteomics, 7 (11), p. 1908-15, 2007.

Résumé | Liens | BibTeX | Étiquettes: blandin, M3i, Proteome

Wang-Sattler, Rui; Blandin, Stephanie A; Ning, Ye; Blass, Claudia; Dolo, Guimogo; Touré, Yeya T; delle Torre, Alessandra; Lanzaro, Gregory C; Steinmetz, Lars M; Kafatos, Fotis C; Zheng, Liangbiao

Mosaic genome architecture of the Anopheles gambiae species complex Article de journal

PLoS ONE, 2 (11), p. e1249, 2007, ISSN: 1932-6203.

Résumé | Liens | BibTeX | Étiquettes: Animals, Anopheles gambiae, Artificial, Bacterial, Biological Evolution, blandin, Chromosomes, Female, Genetic Markers, Genetic Variation, Genome, M3i, Microsatellite Repeats, Mosaicism

2006

Frolet, Cécile; Thoma, Martine; Blandin, Stéphanie A; Hoffmann, Jules A; Levashina, Elena A

Boosting NF-kappaB-dependent basal immunity of Anopheles gambiae aborts development of Plasmodium berghei Article de journal

Immunity, 25 (4), p. 677–685, 2006, ISSN: 1074-7613.

Résumé | Liens | BibTeX | Étiquettes: Animals, Anopheles gambiae, blandin, Gene Expression, Gene Expression Regulation, Genes, hoffmann, Immunity, Insect, M3i, NF-kappa B, Plasmodium berghei, telomerase

2005

Moita, L F; Wang, R; Michel, K; Blandin, Stéphanie A; Zimmermann, T; Levashina, Elena A; Kafatos, Fotis C

In Vivo Identification of Novel Regulators and Conserved Pathways of Phagocytosis in A. gambiae Article de journal

Immunity., 23 (1), p. 65-73, 2005.

Résumé | Liens | BibTeX | Étiquettes: blandin, M3i, RNAi

2004

Blandin, Stéphanie A; Levashina, Elena A

Curing mosquitoes to control malaria ? Article de journal

Med Sci (Paris)., 20 (8-9), p. 740-2, 2004.

Liens | BibTeX | Étiquettes: blandin, M3i, population control

Budd, A; Blandin, Stéphanie A; Levashina, Elena A; Gibson, T J

Bacterial alpha2-macroglobulins: colonization factors acquired by horizontal gene transfer from the metazoan genome ? Article de journal

Genome Biol., 5 (6), p. R38, 2004.

Résumé | Liens | BibTeX | Étiquettes: alpha2-macroglobulins, blandin, M3i

Blandin, Stéphanie A; Levashina, Elena A

Thioester-containing proteins in insect immunity Article de journal

Mol Immunol., 40 (12), p. 903-8, 2004.

Résumé | BibTeX | Étiquettes: blandin, M3i, TEP1

Marco, Valeria De; Stier, Gunter; Blandin, Stephanie A; de Marco, Ario

The solubility and stability of recombinant proteins are increased by their fusion to NusA Article de journal

Biochem. Biophys. Res. Commun., 322 (3), p. 766–771, 2004, ISSN: 0006-291X.

Résumé | Liens | BibTeX | Étiquettes: blandin, Drug Stability, Escherichia coli Proteins, Genetic Vectors, Glutathione Transferase, Kinetics, M3i, Oxidation-Reduction, Peptide Elongation Factors, Recombinant Fusion Proteins, Recombinant Proteins, Solubility, Transcription Factors, Transcriptional Elongation Factors

Blandin, Stephanie A; Shiao, Shin-Hong; Moita, Luis F; Janse, Chris J; Waters, Andrew P; Kafatos, Fotis C; Levashina, Elena A

Complement-like protein TEP1 is a determinant of vectorial capacity in the malaria vector Anopheles gambiae Article de journal

Cell, 116 (5), p. 661–670, 2004, ISSN: 0092-8674.

Résumé | BibTeX | Étiquettes: Animals, Anopheles, blandin, Female, Genetic, Humans, Insect Proteins, Insect Vectors, M3i, Malaria, Models, Molecular, Plasmodium berghei, Polymorphism, Protein Structure, RNA, Sequence Alignment, Tertiary

Blandin, Stéphanie A; Levashina, Elena A

Mosquito immune responses against malaria parasites Article de journal

Curr. Opin. Immunol., 16 (1), p. 16–20, 2004, ISSN: 0952-7915.

Résumé | BibTeX | Étiquettes: Animals, Anopheles, blandin, Gene Library, Genes, Hemocytes, Host-Parasite Interactions, Immunity, Innate, Insect, Insect Vectors, M3i, Malaria, Plasmodium

2003

Goto, Akira; Blandin, Stéphanie A; Royet, Julien; Reichhart, Jean-Marc; Levashina, Elena A

Silencing of Toll pathway components by direct injection of double-stranded RNA into Drosophila adult flies Article de journal

Nucleic Acids Res., 31 (22), p. 6619–6623, 2003, ISSN: 1362-4962.

Résumé | BibTeX | Étiquettes: Animals, blandin, Cell Surface, Double-Stranded, Epistasis, Female, Genetic, Green Fluorescent Proteins, Homeodomain Proteins, Luminescent Proteins, M3i, Phenotype, Receptors, reichhart, RNA, RNA Interference, Serpins, Signal Transduction, Time Factors, Toll-Like Receptors, Transcription Factors

2002

Christophides, George K; Zdobnov, Evgeny; Barillas-Mury, Carolina; Birney, Ewan; Blandin, Stephanie A; Blass, Claudia; Brey, Paul T; Collins, Frank H; Danielli, Alberto; Dimopoulos, George; Hetru, Charles; Hoa, Ngo T; Hoffmann, Jules A; Kanzok, Stefan M; Letunic, Ivica; Levashina, Elena A; Loukeris, Thanasis G; Lycett, Gareth; Meister, Stephan; Michel, Kristin; Moita, Luis F; Müller, Hans-Michael; Osta, Mike A; Paskewitz, Susan M; Reichhart, Jean-Marc; Rzhetsky, Andrey; Troxler, Laurent; Vernick, Kenneth D; Vlachou, Dina; Volz, Jennifer; von Mering, Christian; Xu, Jiannong; Zheng, Liangbiao; Bork, Peer; Kafatos, Fotis C

Immunity-related genes and gene families in Anopheles gambiae Article de journal

Science, 298 (5591), p. 159–165, 2002, ISSN: 1095-9203.

Résumé | Liens | BibTeX | Étiquettes: Alternative Splicing, Animals, Anopheles, Apoptosis, bacteria, bioinformatic, blandin, Catechol Oxidase, Computational Biology, Enzyme Precursors, Gene Expression Regulation, Genes, Genetic, Genome, hoffmann, Immunity, Innate, Insect, Insect Proteins, M3i, Multigene Family, Peptides, Phylogeny, Plasmodium, Protein Structure, reichhart, Selection, Serine Endopeptidases, Serpins, Signal Transduction, Tertiary

Blandin, Stéphanie A; Moita, L F; Kocher, T; Wilm, M; Kafatos, Fotis C; Levashina, Elena A

Reverse genetics in the mosquito, Anopheles gambiae : targeted disruption of the Defensin gene Article de journal

EMBO Rep., 3 (9), p. 852-6, 2002.

Résumé | Liens | BibTeX | Étiquettes: blandin, defensin, M3i

Levashina, Elena A; Blandin, Stéphanie A; Moita, L F; Lagueux, Marie; Kafatos, Fotis C

Thioester-Containing Proteins of Protostomes Book Chapter

Ezekowitz, Alan R B; Hoffmann, Jules A (Ed.): Chapitre Infectious Disease: Innate Immunity., p. 155-173, Humana Press Inc, Totowa, NJ, 2002.

BibTeX | Étiquettes: blandin, M3i, Thioester-Containing Protein

2001

Levashina, Elena A; Moita, L F; Blandin, Stéphanie A; Vriend, G; Lagueux, Marie; Kafatos, F C

Conserved role of a complement-like protein in phagocytosis revealed by dsRNA knockout in cultured cells of the mosquito, Anopheles gambiae Article de journal

Cell, 104 (5), p. 709–718, 2001, ISSN: 0092-8674.

Résumé | BibTeX | Étiquettes: alpha-Macroglobulins, Animals, Anopheles, blandin, Cells, Cloning, Complement C3, Cultured, DNA Fragmentation, Double-Stranded, Female, Genetic, Gram-Negative Bacteria, Hemocytes, Insect Proteins, M3i, Molecular, Nucleic Acid Denaturation, Phagocytosis, Protein Structure, RNA, Tertiary, Transcription