Accès direct Unités de recherche

Publications

Tout voire

2020

Théobald-Dietrich, A; de Wijn, R; Rollet, K; Bluhm, A; Rudinger-Thirion, J; Paulus, C; Lorber, B; Thureau, A; Frugier, M; Sauter, C

Structural Analysis of RNA by Small-Angle X-ray Scattering Book Chapter

Arluison, V; Wien, F (Ed.): RNA Spectroscopy: Methods and Protocols, 2113 , p. 189-215, Springer Protocols, Humana Press, New York, NY, 2020, ISBN: 32006316.

Résumé | Liens | BibTeX | Étiquettes: ERIANI, FRUGIER, FRUGIER IRES Integrative structural biology RNA SEC-SAXS Structure tRNA, Unité ARN

Riley, L G; Rudinger-Thirion, J; Frugier, M; Wilson, M; Luig, M; Alahakoon, T I; Nixon, C Y; Kirk, E P; Roscioli, T; Lunke, S; Stark, Z; Wierenga, K J; Palle, S; Walsh, M; Higgs, E; Arbuckle, S; Thirukeswaran, S; Compton, A G; Thorburn, D R; Christodoulou, J

The Expanding LARS2 Phenotypic Spectrum: HLASA, Perrault Syndrome With Leukodystrophy, and Mitochondrial Myopathy Article de journal

Hum Mutat, 41 (8), p. 1425-1434, 2020, ISBN: 32442335.

Résumé | Liens | BibTeX | Étiquettes: ERIANI, FRUGIER, FRUGIER Perrault syndrome low frequency hearing loss primary ovarian insufficiency sensorineural hearing loss, Unité ARN

2019

Salinas, T; Farouk-Ameqrane, S E; Ubrig, E; Sauter, C; Duchêne, A M; Maréchal-Drouard, L

Molecular basis for the differential interaction of plant mitochondrial VDAC proteins with tRNAs Article de journal

Nucleic Acids Res, 47 (2), p. 1048-1049, 2019, ISBN: 30519697.

Liens | BibTeX | Étiquettes: FRUGIER, Unité ARN

van der Knaap, M S; Bugiani, M; Mendes, M I; Riley, L G; Smith, D E C; Rudinger-Thirion, J; Frugier, M; Breur, M; Crawford, J; van Gaalen, J; Schouten, M; Willems, M; Waisfisz, Q; Mau-Them, F T; Rodenburg, R J; Taft, R J; Keren, B; Christodoulou, J; Depienne, C; Simons, C; Salomons, G S; Mochel, F

Biallelic variants in LARS2 and KARS cause deafness and (ovario)leukodystrophy Article de journal

Neurology, 92 (11), p. e1225-e1237, 2019, ISBN: 30737337.

Résumé | Liens | BibTeX | Étiquettes: ERIANI, FRUGIER, Unité ARN

de Wijn, R; Hennig, O; Roche, J; Engilberge, S; Rollet, K; Fernandez-Millan, P; Brillet, K; Betat, H; Mörl, M; Roussel, A; Girard, E; Mueller-Dieckmann, C; Fox, G C; Olieric, V; Gavira, J A; Lorber, B; Sauter, C

A simple and versatile microfluidic device for efficient biomacromolecule crystallization and structural analysis by serial crystallography Article de journal

IUCrJ, 6 (Pt 3), p. 454-464, 2019, ISBN: 31098026.

Résumé | Liens | BibTeX | Étiquettes: ENNIFAR, FRUGIER, FRUGIER ENNIFAR ChipX3 counter-diffusion crystallization ligand soaking macromolecule microfluidics protein structure room temperature seeding serial crystallography trace fluorescent labeling, Unité ARN

2018

Riley, L G; Heeney, M M; Rudinger-Thirion, J; Frugier, M; Campagna, D R; Zhou, R; Hale, G A; Hilliard, L M; Kaplan, J A; Kwiatkowski, J L; Sieff, C A; Steensma, D P; Rennings, A J; Simons, A; Schaap, N; Roodenburg, R J; Kleefstra, T; Arenillas, L; Fita-Torró, J; Ahmed, R; Abboud, M; Bechara, E; Farah, R; Tamminga, R Y; Bottomley, S S; Sanchez, M; Swinkels, D W; Christodoulou, J; Fleming, M D

The phenotypic spectrum of germline YARS2 variants: from isolated sideroblastic anemia to mitochondrial myopathy, lactic acidosis and sideroblastic anemia 2 Article de journal

Haematologica, 103 (12), p. 2008-2015, 2018, ISBN: 30026338.

Résumé | Liens | BibTeX | Étiquettes: ERIANI, FRUGIER, FRUGIER Congenital sideroblastic anemia MLASA YARS2 mitochondrial myopathy sideroblastic anemia, Unité ARN

Cela, M; Paulus, C; Santos, M A S; Moura, G R; Frugier, M; Rudinger-Thirion, J

Plasmodium apicoplast tyrosyl-tRNA synthetase recognizes an unusual, simplified identity set in cognate tRNATyr Article de journal

PLoS One, 13 (12), p. e0209805, 2018, ISBN: 30592748.

Résumé | Liens | BibTeX | Étiquettes: ERIANI, FRUGIER, Unité ARN

2017

Schellenberger, P; Sauter, C; Lorber, B; Bron, P; Trapani, S; Bergdoll, M; Marmonier, A; Schmitt-Kelchinger, C; Lemaire, O; Demangeat, G; Ritzenthaler, C

Correction: Structural Insights into Viral Determinants of Nematode Mediated Grapevine fanleaf virus Transmission. Article de journal

PLoS Pathog, 13 (3), p. e1006268, 2017, ISBN: 28296962.

Résumé | Liens | BibTeX | Étiquettes: FRUGIER, Unité ARN

2016

Riley, L G; Rudinger-Thirion, J; Schmitz-Abe, K; Thorburn, D R; Davis, R L; Teo, J; Arbuckle, S; Cooper, S T; Campagna, D R; Frugier, M; Markianos, K; Sue, C M; Fleming, M D; Christodoulou, J

LARS2 Variants Associated with Hydrops, Lactic Acidosis, Sideroblastic Anemia, and Multisystem Failure. Book Chapter

Morava, E (Ed.): JIMD Rep, 28 , p. 49-57, Springer, SSIEM, 2016, ISBN: 26537577.

Résumé | Liens | BibTeX | Étiquettes: ERIANI, FRUGIER, Unité ARN

Kapps, D; Cela, M; Théobald-Dietrich, A; Hendrickson, T; Frugier, M

OB or Not OB: Idiosyncratic utilization of the tRNA-binding OB-fold domain in unicellular, pathogenic eukaryotes. Article de journal

FEBS Lett, 590 (23), p. 4180-4191, 2016, ISBN: 27714804.

Résumé | Liens | BibTeX | Étiquettes: ERIANI, FRUGIER, FRUGIER Trbp111 parasites pathogenic eukaryotes tRNA binding protein, Unité ARN

Bour, T; Mahmoudi, N; Kapps, D; Thiberge, S; Bargieri, D; Ménard, R; Frugier, M

Apicomplexa-specific tRip facilitates import of exogenous tRNAs into malaria parasites Article de journal

Proc Natl Acad Sci U S A, 113 (17), p. 4717-4722, 2016, ISBN: 27071116.

Résumé | Liens | BibTeX | Étiquettes: ERIANI, FRUGIER, FRUGIER Plasmodium tRNA trafficking, Unité ARN

2015

Alexandrova, J; Paulus, C; Rudinger-Thirion, J; Jossinet, F; Frugier, M

Elaborate uORF/IRES features control expression and localization of human glycyl-tRNA synthetase. Article de journal

RNA Biol, 12 (12), p. 1301-1313, 2015, ISBN: 26327585.

Résumé | Liens | BibTeX | Étiquettes: ERIANI, FRUGIER, FRUGIER JOSSINET Aminoacyl-tRNA synthetase IRES post-transcriptional control uORF, Unité ARN

2011

Rudinger-Thirion, J; Lescure, A; Paulus, C; Frugier, M

Misfolded human tRNA isodecoder binds and neutralizes a 3' UTR-embedded Alu element Article de journal

Proc Natl Acad Sci U S A, 108 (40), p. E794-802, 2011, ISSN: 1091-6490 (Electronic) 0027-8424 (Linking), (Rudinger-Thirion, Joelle Lescure, Alain Paulus, Caroline Frugier, Magali United States Proceedings of the National Academy of Sciences of the United States of America Proc Natl Acad Sci U S A. 2011 Oct 4;108(40):E794-802. Epub 2011 Sep 6.).

Résumé | Liens | BibTeX | Étiquettes: ERIANI, FRUGIER, LESCURE, Unité ARN

2009

Bour, T; Akaddar, A; Lorber, B; Blais, S; Balg, C; Candolfi, E; Frugier, M

Plasmodial aspartyl-tRNA synthetases and peculiarities in Plasmodium falciparum Article de journal

J Biol Chem, 284 (28), p. 18893-18903, 2009, ISBN: 19443655, (0021-9258 (Print) 0021-9258 (Linking) Journal Article Research Support, Non-U.S. Gov't).

Résumé | Liens | BibTeX | Étiquettes: Amino Acid, ERIANI, FRUGIER, FRUGIER FLORENTZ Amino Acid Sequence Amino Acids/chemistry Animals Aspartate-tRNA Ligase/*metabolism Aspartic Acid/chemistry Base Sequence Cloning, Molecular Cytoplasm/metabolism Dimerization Fungal Proteins/chemistry Humans Kinetics Molecular Sequence Data Plasmodium falciparum Protein Structure, Tertiary Sequence Homology, Unité ARN

2008

Ryckelynck, M; Paulus, C A; Frugier, M

Post-Translational Modifications Guard Yeast from Misaspartylation Article de journal

Biochemistry, 47 (47), p. 12476-12482, 2008, ISBN: 18956891, (1520-4995 (Electronic) 0006-2960 (Linking) Journal article).

Résumé | Liens | BibTeX | Étiquettes: ERIANI, FRUGIER, RYCKELYNCK, Unité ARN

2005

Ryckelynck, M; Masquida, B; Giege, R; Frugier, M

An intricate RNA structure with two tRNA-derived motifs directs complex formation between yeast aspartyl-tRNA synthetase and its mRNA Article de journal

J Mol Biol, 354 (3), p. 614-629, 2005, ISBN: 16257416, (0022-2836 (Print) Journal Article).

Résumé | Liens | BibTeX | Étiquettes: ERIANI, FRUGIER, Messenger/*chemistry/*metabolism RNA, Molecular Molecular Sequence Data Nucleic Acid Conformation Protein Structure, Non-U.S. Gov't Saccharomyces cerevisiae/*enzymology/*genetics Sequence Alignment Sequence Homology, Nucleic Acid Solubility, RYCKELYNCK, Tertiary RNA, Transfer/*chemistry/*metabolism Research Support, Unité ARN, WESTHOF GIEGE FRUGIER Aspartate-tRNA Ligase/genetics/*metabolism Base Sequence DNA Footprinting Gene Deletion Models

Ryckelynck, M; Giege, R; Frugier, M

tRNAs and tRNA mimics as cornerstones of aminoacyl-tRNA synthetase regulations Article de journal

Biochimie, 87 (9-10), p. 835-845, 2005, ISBN: 15925436, (0300-9084 Journal article).

Résumé | Liens | BibTeX | Étiquettes: ERIANI, FRUGIER, GIEGE FRUGIER, RYCKELYNCK, Unité ARN

Frugier, M; Ryckelynck, M; Giege, R

tRNA-balanced expression of a eukaryal aminoacyl-tRNA synthetase by an mRNA-mediated pathway Article de journal

EMBO Rep, 6 (9), p. 860-865, 2005, ISBN: 16113655, (1469-221x Journal article).

Résumé | Liens | BibTeX | Étiquettes: ERIANI, FRUGIER, GIEGE FRUGIER, RYCKELYNCK, Unité ARN

Bonnefond, L; Frugier, M; Giege, R; Rudinger-Thirion, J

Human mitochondrial TyrRS disobeys the tyrosine identity rules Article de journal

RNA, 11 (5), p. 558-562, 2005, ISBN: 15840810, (1355-8382 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: ERIANI, FRUGIER, GIEGE FRUGIER Amino Acid Sequence Base Sequence Catalytic Domain Humans Mitochondria/*enzymology Molecular Sequence Data RNA, Non-U.S. Gov't Substrate Specificity Tyrosine/genetics/*metabolism Tyrosine-tRNA Ligase/chemistry/*metabolism, Transfer, Tyr/genetics/*metabolism Research Support, Unité ARN

Ambrogelly, A; Frugier, M; Ibba, M; Soll, D; Giege, R

Transfer RNA recognition by class I lysyl-tRNA synthetase from the Lyme disease pathogen Borrelia burgdorferi Article de journal

FEBS Lett, 579 (12), p. 2629-2634, 2005, ISBN: 15862301, (0014-5793 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: ERIANI, FRUGIER, GIEGE FRUGIER, Unité ARN

2004

Théobald-Dietrich, A; Frugier, M; Giege, R; Rudinger-Thirion, J

Atypical archaeal tRNA pyrrolysine transcript behaves towards EF-Tu as a typical elongator tRNA Article de journal

Nucleic Acids Res, 32 (3), p. 1091-1096, 2004, ISBN: 14872064, (1362-4962 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Archaeal/chemistry/*metabolism RNA, ERIANI, FRUGIER, GIEGE Anticodon/metabolism Base Sequence Lysine/*analogs & derivatives/*metabolism Lysine-tRNA Ligase/metabolism Methanosarcina barkeri/genetics Mitochondria/genetics Molecular Sequence Data Nucleic Acid Conformation Peptide Elongation Factor Tu/*metabolism RNA, Non-U.S. Gov't Yeasts/enzymology, Ser/chemistry Selenocysteine/metabolism Support, Transfer, Transfer/chemistry/*metabolism RNA, Unité ARN

Sissler, M; Helm, M; Frugier, M; Giege, R; Florentz, C

Aminoacylation properties of pathology-related human mitochondrial tRNA(Lys) variants Article de journal

RNA, 10 (5), p. 841-853, 2004, ISBN: 15100439, (1355-8382 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: ERIANI, FLORENTZ, FLORENTZ GIEGE Acylation Aminoacyltransferases/*genetics Human MERRF Syndrome/genetics Mitochondria/*genetics Mitochondrial Diseases/*genetics Mutation Nucleic Acid Conformation RNA, FRUGIER, Lys/*genetics Sequence Analysis, Non-U.S. Gov't Variation (Genetics), RNA Support, SISSLER, Transfer, Unité ARN

2003

Sohm, B; Frugier, M; Brule, H; Olszak, K; Przykorska, A; Florentz, C

Towards understanding human mitochondrial leucine aminoacylation identity Article de journal

J Mol Biol, 328 (5), p. 995-1010, 2003, ISBN: 12729737, (0022-2836 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Base Sequence Human In Vitro Leucine/*metabolism Leucine-tRNA Ligase/*metabolism Mitochondria/*metabolism Mitochondrial Diseases/genetics/metabolism Molecular Sequence Data Mutation Nucleic Acid Conformation RNA, ERIANI, FLORENTZ, FRUGIER, Leu/chemistry/genetics/*metabolism Recombinant Proteins/genetics/metabolism Solutions Substrate Specificity Support, Non-U.S. Gov't Variation (Genetics), Transfer, Unité ARN

Ryckelynck, M; Giege, R; Frugier, M

Yeast tRNA(Asp) charging accuracy is threatened by the N-terminal extension of aspartyl-tRNA synthetase Article de journal

J Biol Chem, 278 (11), p. 9683-9690, 2003, ISBN: 12486031, (0021-9258 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Amino Acid Motifs Aspartate-tRNA Ligase/*metabolism Aspartic Acid/chemistry Base Sequence Codon Escherichia coli/metabolism Kinetics Molecular Sequence Data Nucleic Acid Conformation Nucleic Acids/chemistry Protein Structure, Asp/*chemistry Support, ERIANI, FRUGIER, Messenger/metabolism RNA, Non-U.S. Gov't Yeasts/metabolism, RYCKELYNCK, Secondary Protein Structure, Tertiary RNA, Transfer, Unité ARN

Giege, R; Frugier, M

Transfer RNA Structure and Identity Book Chapter

Lapointe, J; Brakier-Gringas, L (Ed.): Translation mechanisms, p. 1-24, Landes Bioscience, 2003.

Résumé | Liens | BibTeX | Étiquettes: ERIANI, FRUGIER, Unité ARN

Frugier, M; Giege, R; Schimmel, P

RNA recognition by designed peptide fusion creates "artificial" tRNA synthetase Article de journal

Proc Natl Acad Sci U S A, 100 (13), p. 7471-7475, 2003, ISBN: 12796515, (0027-8424 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Amino Acid Motifs Amino Acid Sequence Amino Acyl-tRNA Ligases/*chemistry Base Sequence Binding Sites Catalytic Domain Escherichia coli/genetics/metabolism *Genetic Techniques Kinetics Models, ERIANI, FRUGIER, Genetic Molecular Sequence Data Mutation Nucleic Acid Conformation Peptides/*chemistry Protein Binding Protein Structure, Non-U.S. Gov't Support, P.H.S. Time Factors, Tertiary RNA/chemistry Recombinant Fusion Proteins/metabolism Support, U.S. Gov't, Unité ARN

Frugier, M; Giege, R

Yeast aspartyl-tRNA synthetase binds specifically its own mRNA Article de journal

J Mol Biol, 331 (2), p. 375-383, 2003, ISBN: 12888345, (0022-2836 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: 5' Untranslated Regions Amino Acid Motifs Aspartate-tRNA Ligase/*chemistry/metabolism Binding, Competitive Blotting, Drug Gene Expression Regulation, Enzymologic Genes, ERIANI, FRUGIER, Fungal Kinetics Luminescent Proteins/metabolism Plasmids Protein Binding Protein Structure, Messenger/metabolism RNA, Non-U.S. Gov't, Tertiary RNA/metabolism RNA, Transfer/metabolism Saccharomyces cerevisiae/metabolism Support, Unité ARN, Western Dose-Response Relationship

2000

Frugier, M; Moulinier, L; Giege, R

A domain in the N-terminal extension of class IIb eukaryotic aminoacyl-tRNA synthetases is important for tRNA binding Article de journal

EMBO J, 19 (10), p. 2371-2380, 2000, ISBN: 10811628, (0261-4189 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Amino Acid Sequence Amino Acyl-tRNA Ligases/chemistry/*metabolism Aspartate-tRNA Ligase/chemistry/metabolism Molecular Sequence Data RNA, ERIANI, FRUGIER, Fungal/metabolism RNA, Non-U.S. Gov't, Transfer/*metabolism Saccharomyces cerevisiae/*metabolism Sequence Alignment Support, Unité ARN

1994

Frugier, M; Soll, D; Giege, R; Florentz, C

Identity switches between tRNAs aminoacylated by class I glutaminyl- and class II aspartyl-tRNA synthetases Article de journal

Biochemistry, 33 (33), p. 9912-9921, 1994, ISBN: 8060999, (0006-2960 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Acylation Aspartate-tRNA Ligase/chemistry/*metabolism Base Sequence Crystallization Escherichia coli/*enzymology/genetics Glutamate-tRNA Ligase/chemistry/*metabolism Kinetics Molecular Sequence Data Molecular Structure Mutation Nucleic Acid Conformation RNA, Asp/chemistry/*metabolism RNA, ERIANI, FLORENTZ, FRUGIER, Gln/chemistry/*metabolism Saccharomyces cerevisiae/*enzymology/genetics Support, Non-U.S. Gov't Support, P.H.S., Transfer, U.S. Gov't, Unité ARN

Frugier, M; Florentz, C; Hosseini, M W; Lehn, J M; Giege, R

Synthetic polyamines stimulate in vitro transcription by T7 RNA polymerase Article de journal

Nucleic Acids Res, 22 (14), p. 2784-2790, 1994, ISBN: 8052534, (0305-1048 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Bacteriophage T7/enzymology Base Sequence Comparative Study DNA-Directed RNA Polymerases/drug effects/*metabolism Kinetics Molecular Sequence Data Molecular Structure Nucleic Acid Conformation Oligodeoxyribonucleotides Polyamines/chemistry/*pharmacology Promoter Regions (Genetics) RNA, ERIANI, FLORENTZ, FRUGIER, Genetic Transcription, Genetic/*drug effects, Non-U.S. Gov't Templates, Transfer, Unité ARN, Val/*biosynthesis/chemistry Structure-Activity Relationship Support

Frugier, M; Florentz, C; Giege, R

Efficient aminoacylation of resected RNA helices by class II aspartyl-tRNA synthetase dependent on a single nucleotide Article de journal

EMBO J, 13 (9), p. 2218-2226, 1994, ISBN: 8187774, (0261-4189 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Acylation Anticodon Aspartate-tRNA Ligase/*metabolism Aspartic Acid/metabolism Base Sequence Evolution Molecular Sequence Data Nucleic Acid Conformation RNA, ERIANI, FLORENTZ, FRUGIER, Fungal/chemistry/*metabolism Substrate Specificity Support, Non-U.S. Gov't, Unité ARN

1993

Frugier, M; Florentz, C; Schimmel, P; Giege, R

Triple aminoacylation specificity of a chimerized transfer RNA Article de journal

Biochemistry, 32 (50), p. 14053-14061, 1993, ISBN: 8268184, (0006-2960 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: Acylation Alanine/metabolism Base Sequence Chimera Escherichia coli/genetics Molecular Sequence Data Mutation Nucleic Acid Conformation Phenylalanine/metabolism RNA, Asp/chemistry/genetics/*metabolism Saccharomyces cerevisiae/genetics Support, ERIANI, FLORENTZ, FRUGIER, Non-U.S. Gov't Support, P.H.S. Valine/metabolism, Transfer, U.S. Gov't, Unité ARN

1992

Frugier, M; Florentz, C; Giege, R

Anticodon-independent aminoacylation of an RNA minihelix with valine Article de journal

Proc Natl Acad Sci U S A, 89 (9), p. 3990-3994, 1992, ISBN: 1570324, (0027-8424 Journal Article).

Résumé | Liens | BibTeX | Étiquettes: *Amino Acid Activation Anticodon Base Sequence Hydrogen Bonding In Vitro Molecular Sequence Data RNA, ERIANI, FLORENTZ, FRUGIER, Non-U.S. Gov't Valine-tRNA Ligase/*metabolism, Transfer, Unité ARN, Val/chemistry/*metabolism Saccharomyces cerevisiae Structure-Activity Relationship Support