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2019

Franchet, Adrien; Niehus, Sebastian; Caravello, Gaetan; Ferrandon, Dominique

Phosphatidic acid as a limiting host metabolite for the proliferation of the microsporidium Tubulinosema ratisbonensis in Drosophila flies Article de journal

Nature Microbiology, 4 (4), p. 645, 2019, ISBN: 2058-5276.

Résumé | Liens | BibTeX | Étiquettes: Drosophila, ferrandon, Host-Parasite Interactions, Lipids, M3i, metabolism, microsporidia

2018

Haller, Samantha; Franchet, Adrien; Hakkim, A; Chen, J; Drenkard, E; Yu, S; Schirmeier, Steffi; Li, Zi; Martins, Nelson; Ausubel, FM; Liégeois, Samuel; Ferrandon, Dominique

Quorum-sensing regulator RhlR but not its autoinducer RhlI enables Pseudomonas to evade opsonization Article de journal

EMBO Reports, 2018.

Liens | BibTeX | Étiquettes: Drosophila, ferrandon, M3i, Opsonin Proteins, Phagocytosis, Pseudomonas aeruginosa, Quorum Sensing

2016

Lee, Kwang-Zin; Lestradet, Matthieu; Socha, Catherine; Schirmeier, Stefanie; Schmitz, Antonin; Spenlé, Caroline; Lefebvre, Olivier; Keime, Céline; Yamba, Wennida M.; Bou Aoun, Richard; Liegeois, Samuel; Schwab, Yannick; Simon-Assmann, Patricia; Dalle, Frédéric; Ferrandon, Dominique

Enterocyte Purge and Rapid Recovery Is a Resilience Reaction of the Gut Epithelium to Pore-Forming Toxin Attack Article de journal

Cell Host & Microbe, 2016, ISSN: 1931-3128.

Résumé | Liens | BibTeX | Étiquettes: Epithelium, ferrandon, gut, M3i, resilience

2015

Brunke, Sascha; Quintin, Jessica; Kasper, Lydia; Jacobsen, Ilse D; Richter, Martin E; Hiller, Ekkehard; Schwarzmüller, Tobias; d'Enfert, Christophe; Kuchler, Karl; Rupp, Steffen; Hube, Bernhard; Ferrandon, Dominique

Of mice, flies--and men? Comparing fungal infection models for large-scale screening efforts Article de journal

Dis Model Mech, 8 (5), p. 473–486, 2015, ISSN: 1754-8411.

Résumé | Liens | BibTeX | Étiquettes: Alternative infection models, Candida glabrata, ferrandon, Fungal virulence factors, M3i, Mutant library, Signature-tagged mutagenesis

2014

Amcheslavsky, Alla; Song, Wei; Li, Qi; Nie, Yingchao; Bragatto, Ivan; Ferrandon, Dominique; Perrimon, Norbert; Ip, Tony Y

Enteroendocrine cells support intestinal stem-cell-mediated homeostasis in Drosophila Article de journal

Cell Rep, 9 (1), p. 32–39, 2014, ISSN: 2211-1247.

Résumé | Liens | BibTeX | Étiquettes: Animals, Cell Differentiation, Enterocytes, Enteroendocrine Cells, Female, ferrandon, Homeostasis, Intestines, M3i, Male, Stem Cells, Tachykinins

Haller, Samantha; Limmer, Stefanie; Ferrandon, Dominique

Assessing Pseudomonas virulence with a nonmammalian host: Drosophila melanogaster Article de journal

Methods Mol. Biol., 1149 , p. 723–740, 2014, ISSN: 1940-6029.

Résumé | Liens | BibTeX | Étiquettes: Animal, Animals, Antimicrobial Cationic Peptides, Biological Assay, Colony Count, Disease Models, ferrandon, Hemolymph, Host-Pathogen Interactions, M3i, Mammals, Microbial, Pseudomonas aeruginosa, Pseudomonas Infections, Reverse Transcriptase Polymerase Chain Reaction, Virulence

Lestradet, Matthieu; Lee, Kwan Zin; Ferrandon, Dominique

Drosophila as a model for intestinal infections Article de journal

Methods Mol Biol, 1197 , p. 11–40, 2014, ISSN: 1940-6029 (Electronic) 1064-3745 (Linking).

Résumé | Liens | BibTeX | Étiquettes: Animal, Animals, Bacterial Physiological Phenomena, Disease Models, ferrandon, Gastrointestinal Tract, Host-Pathogen Interactions, M3i

Schwarzmüller, Tobias; Ma, Biao; Hiller, Ekkehard; Istel, Fabian; Tscherner, Michael; Brunke, Sascha; Ames, Lauren; Firon, Arnaud; Green, Brian; Cabral, Vitor; Marcet-Houben, Marina; Jacobsen, Ilse D; Quintin, Jessica; Seider, Katja; Frohner, Ingrid; Glaser, Walter; Jungwirth, Helmut; Bachellier-Bassi, Sophie; Chauvel, Murielle; Zeidler, Ute; Ferrandon, Dominique; Gabaldón, Toni; Hube, Bernhard; d'Enfert, Christophe; Rupp, Steffen; Cormack, Brendan; Haynes, Ken; Kuchler, Karl

Systematic phenotyping of a large-scale Candida glabrata deletion collection reveals novel antifungal tolerance genes Article de journal

PLoS Pathog., 10 (6), p. e1004211, 2014, ISSN: 1553-7374.

Résumé | Liens | BibTeX | Étiquettes: Antifungal Agents, Azoles, Biofilms, Candida glabrata, Candidiasis, Cell Wall, Drug Resistance, Echinocandins, ferrandon, Fungal, Fungal Proteins, Gene Deletion, Gene Knockout Techniques, Gene Library, M3i, Microbial Sensitivity Tests, Osmotic Pressure, Phenotype

2013

Quintin, Jessica; Asmar, Joelle; Matskevich, Alexey A; Lafarge, Marie-Céline; Ferrandon, Dominique

The Drosophila Toll pathway controls but does not clear Candida glabrata infections Article de journal

J. Immunol., 190 (6), p. 2818–2827, 2013, ISSN: 1550-6606.

Résumé | Liens | BibTeX | Étiquettes: Adaptor Proteins, Animal, Animals, Antigens, Candida glabrata, Candidiasis, Cells, Cultured, Differentiation, Disease Models, ferrandon, Immunologic, M3i, Phagocytosis, Receptors, Signal Transducing, Signal Transduction, Toll-Like Receptors, Virulence

Ferrandon, Dominique

The complementary facets of epithelial host defenses in the genetic model organism Drosophila melanogaster: from resistance to resilience Article de journal

Curr. Opin. Immunol., 25 (1), p. 59–70, 2013, ISSN: 1879-0372.

Résumé | Liens | BibTeX | Étiquettes: Adult Stem Cells, aging, Animal, Animals, Cell Proliferation, Disease Models, Enterocytes, ferrandon, Humans, Immunity, Intestinal Mucosa, M3i, Metagenome, Stem Cell Niche, Wound Healing

Ayyaz, Arshad; Giammarinaro, Philippe; Liégeois, Samuel; Lestradet, Matthieu; Ferrandon, Dominique

A negative role for MyD88 in the resistance to starvation as revealed in an intestinal infection of Drosophila melanogaster with the Gram-positive bacterium Staphylococcus xylosus Article de journal

Immunobiology, 218 (4), p. 635–644, 2013, ISSN: 1878-3279.

Résumé | Liens | BibTeX | Étiquettes: Adaptor Proteins, Animal, Animals, Antigens, Differentiation, Disease Models, ferrandon, Immunity, Immunologic, Innate, Intestinal Diseases, M3i, Mucosal, Mutation, Receptors, Signal Transducing, Staphylococcal Infections, Staphylococcus, Starvation, Toll-Like Receptors

2012

Ezekowitz, Alan R B; Dimarcq, Jean-Luc; Kafatos, Fotis; Levashina, Elena A; Ferrandon, Dominique; Hetru, Charles; Imler, Jean-Luc; Reichhart, Jean-Marc

Lawrence's book review unfair to Hoffmann Article de journal

Curr. Biol., 22 (12), p. R482, 2012, ISSN: 1879-0445.

Liens | BibTeX | Étiquettes: Book Reviews as Topic, Ethics, ferrandon, imler, M3i, Professional, reichhart

Niehus, Sebastian; Giammarinaro, Philippe; Liégeois, Samuel; Quintin, Jessica; Ferrandon, Dominique

Fly culture collapse disorder: detection, prophylaxis and eradication of the microsporidian parasite Tubulinosema ratisbonensis infecting Drosophila melanogaster Article de journal

Fly (Austin), 6 (3), p. 193–204, 2012, ISSN: 1933-6942.

Résumé | Liens | BibTeX | Étiquettes: Animals, Apansporoblastina, Apansporoblastina/*genetics/physiology, Base Sequence, cure, Disinfection, Disinfection/methods, DNA, DNA Primers, Drosophila melanogaster/*microbiology, ferrandon, fumagillin, Fungal, Fungal/chemistry, M3i, microsporidia, obligate intracellular parasitism, PCR detection, Phylogeny, Polymerase Chain Reaction, Polymerase Chain Reaction/methods, prophylaxis, Ribosomal, Ribosomal/chemistry, Sequence Alignment, Tubulinosema ratisbonensis

Meister, Marie; Ferrandon, Dominique

Immune cell transdifferentiation: a complex crosstalk between circulating immune cells and the haematopoietic niche Article de journal

EMBO Rep., 13 (1), p. 3–4, 2012, ISSN: 1469-3178.

Liens | BibTeX | Étiquettes: Animals, Cell Communication, Cell Transdifferentiation, ferrandon, Hematopoietic Stem Cells, Humans, Immune System, M3i, Signal Transduction, Stem Cell Niche

2011

Imler, Jean-Luc; Ferrandon, Dominique

[Innate immunity crowned 2011 Nobel Prize winner] Article de journal

Med Sci (Paris), 27 , p. 1019–24, 2011, ISSN: 0767-0974 (Print) 0767-0974 (Linking).

Liens | BibTeX | Étiquettes: *Immunity, *Nobel Prize, Biological, ferrandon, Genetic Association Studies, Humans, imler, Immunotherapy/methods/trends, Innate/genetics, M3i, Models, Molecular Targeted Therapy/trends, Seasons, Structure-Activity Relationship, Toll-Like Receptors/chemistry/genetics/isolation & purification/physiology

Limmer, Stefanie; Haller, Samantha; Drenkard, Eliana; Lee, Janice; Yu, Shen; Kocks, Christine; Ausubel, Frederick M; Ferrandon, Dominique

Pseudomonas aeruginosa RhlR is required to neutralize the cellular immune response in a Drosophila melanogaster oral infection model Article de journal

Proc. Natl. Acad. Sci. U.S.A., 108 (42), p. 17378–17383, 2011, ISSN: 1091-6490.

Résumé | Liens | BibTeX | Étiquettes: Animal, Animals, Bacteremia, Bacterial Proteins, Cellular, Disease Models, ferrandon, Genes, Genetically Modified, Hemolymph, Host-Pathogen Interactions, Immunity, Insect, M3i, Mutation, Oral, Pseudomonas aeruginosa, Pseudomonas Infections, Quorum Sensing, Trans-Activators, Viral, Virulence

Limmer, Stefanie; Quintin, Jessica; Hetru, Charles; Ferrandon, Dominique

Virulence on the fly: Drosophila melanogaster as a model genetic organism to decipher host-pathogen interactions Article de journal

Curr Drug Targets, 12 (7), p. 978–999, 2011, ISSN: 1873-5592.

Résumé | BibTeX | Étiquettes: Animal, Animals, Anti-Infective Agents, Disease Models, Drug Delivery Systems, Drug Design, Drug Resistance, ferrandon, Fungi, High-Throughput Screening Assays, Host-Pathogen Interactions, Humans, M3i, Microbial, Pseudomonas aeruginosa

Aoun, Richard Bou; Hetru, Charles; Troxler, Laurent; Doucet, Daniel; Ferrandon, Dominique; Matt, Nicolas

Analysis of thioester-containing proteins during the innate immune response of Drosophila melanogaster Article de journal

J Innate Immun, 3 (1), p. 52–64, 2011, ISSN: 1662-8128.

Résumé | Liens | BibTeX | Étiquettes: Animals, bioinformatic, DNA, Evolution, ferrandon, Gene Expression Regulation, Hemocytes, Immunity, In Situ Hybridization, Innate, M3i, matt, Molecular, Mutation, Phylogeny, Sequence Analysis

Meister, Marie; Ferrandon, Dominique

Immune cell transdifferentiation: a complex crosstalk between circulating immune cells and the haematopoietic niche Article de journal

EMBO Rep, 13 , p. 3–4, 2011, ISSN: 1469-3178 (Electronic) 1469-221X (Linking).

Liens | BibTeX | Étiquettes: ferrandon, M3i

Lee, Kwang-Zin; Ferrandon, Dominique

Negative regulation of immune responses on the fly Article de journal

EMBO J., 30 (6), p. 988–990, 2011, ISSN: 1460-2075.

Liens | BibTeX | Étiquettes: *Gene Expression Regulation, *Homeostasis, Animals, bacteria, Bacteria/*immunology, Biological, Drosophila melanogaster/*immunology, Drosophila Proteins/biosynthesis/metabolism, ferrandon, Gene Expression Regulation, Homeostasis, M3i, Mitogen-Activated Protein Kinases, Mitogen-Activated Protein Kinases/metabolism, Models, NF-kappa B, NF-kappa B/metabolism, ras Proteins, ras Proteins/metabolism, Receptor Protein-Tyrosine Kinases, Receptor Protein-Tyrosine Kinases/metabolism

Nehme, Nadine T; Quintin, Jessica; Cho, Ju Hyun; Lee, Janice; Lafarge, Marie-Céline; Kocks, Christine; Ferrandon, Dominique

Relative roles of the cellular and humoral responses in the Drosophila host defense against three gram-positive bacterial infections Article de journal

PLoS ONE, 6 (3), p. e14743, 2011, ISSN: 1932-6203.

Résumé | Liens | BibTeX | Étiquettes: Animals, Antimicrobial Cationic Peptides, Carrier Proteins, Cell Surface, Cellular, Enterococcus faecalis, ferrandon, Gram-Positive Bacteria, Gram-Positive Bacterial Infections, Host-Pathogen Interactions, Humoral, Immunity, Innate, M3i, Micrococcus luteus, Opsonin Proteins, Phagocytosis, Receptors, Signal Transduction, Solubility, Staphylococcus aureus

2010

Matskevich, Alexey A; Quintin, Jessica; Ferrandon, Dominique

The Drosophila PRR GNBP3 assembles effector complexes involved in antifungal defenses independently of its Toll-pathway activation function Article de journal

Eur. J. Immunol., 40 (5), p. 1244–1254, 2010, ISSN: 1521-4141.

Résumé | Liens | BibTeX | Étiquettes: Agglutination, Animals, Beauveria, Beauveria/immunology, Candida albicans, Candida albicans/immunology, Carrier Proteins, Carrier Proteins/*immunology/pharmacology, Drosophila melanogaster/*immunology/microbiology, Drosophila Proteins/*immunology/pharmacology/physiology, Enzyme Activation, ferrandon, Fungal, Fungi, Fungi/*immunology, Hemolymph, Hemolymph/immunology, M3i, Melanins, Melanins/*physiology, Monophenol Monooxygenase, Monophenol Monooxygenase/physiology, Multiprotein Complexes, Multiprotein Complexes/physiology, Recombinant Fusion Proteins, Recombinant Fusion Proteins/pharmacology, Serpins, Serpins/physiology, Spores, Toll-Like Receptors, Toll-Like Receptors/immunology

Pospisilik, Andrew J; Schramek, Daniel; Schnidar, Harald; Cronin, Shane J F; Nehme, Nadine T; Zhang, Xiaoyun; Knauf, Claude; Cani, Patrice D; Aumayr, Karin; Todoric, Jelena; Bayer, Martina; Haschemi, Arvand; Puviindran, Vijitha; Tar, Krisztina; Orthofer, Michael; Neely, Gregory G; Dietzl, Georg; Manoukian, Armen; Funovics, Martin; Prager, Gerhard; Wagner, Oswald; Ferrandon, Dominique; Aberger, Fritz; Hui, Chi-chung; Esterbauer, Harald; Penninger, Josef M

Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate Article de journal

Cell, 140 (1), p. 148–160, 2010, ISSN: 1097-4172.

Résumé | Liens | BibTeX | Étiquettes: Adipocytes, Adipogenesis, Animals, Brown, Brown/metabolism, Cyclic AMP, Cyclic AMP/metabolism, Drosophila Proteins/*metabolism, ferrandon, Glucocorticoids, Glucocorticoids/metabolism, Hedgehog Proteins, Hedgehog Proteins/*metabolism, Humans, Knockout, M3i, Mice, Muscle Cells, Muscle Cells/metabolism, Obesity, Obesity/*genetics, Repressor Proteins, Repressor Proteins/genetics, White, White/metabolism

2009

Mishima, Yumiko; Quintin, Jessica; Aimanianda, Vishukumar; Kellenberger, Christine; Coste, Franck; Clavaud, Cecile; Hetru, Charles; Hoffmann, Jules A; Latgé, Jean-Paul; Ferrandon, Dominique; Roussel, Alain

The N-terminal domain of Drosophila Gram-negative binding protein 3 (GNBP3) defines a novel family of fungal pattern recognition receptors Article de journal

J. Biol. Chem., 284 (42), p. 28687–28697, 2009, ISSN: 1083-351X.

Résumé | Liens | BibTeX | Étiquettes: Animals, beta-Glucans, Bombyx, Carrier Proteins, Crystallography, ferrandon, Fungal Proteins, Hemolymph, hoffmann, ligands, M3i, Molecular Conformation, Mutagenesis, Polysaccharides, Protein Structure, Secondary, Tertiary, X-Ray

Ferrandon, Dominique

Host tolerance versus resistance and microbial virulence in the host-pathogen equation Article de journal

Cell Host Microbe, 6 (3), p. 203–205, 2009, ISSN: 1934-6069.

Résumé | Liens | BibTeX | Étiquettes: Animals, ferrandon, Host-Pathogen Interactions, Immune Tolerance, M3i, Salmonella typhimurium, Virulence

Cronin, Shane J F; Nehme, Nadine T; Limmer, Stefanie; Liegeois, Samuel; Pospisilik, Andrew J; Schramek, Daniel; Leibbrandt, Andreas; de Simoes, Ricardo Matos; Gruber, Susanne; Puc, Urszula; Ebersberger, Ingo; Zoranovic, Tamara; Neely, Gregory G; von Haeseler, Arndt; Ferrandon, Dominique; Penninger, Josef M

Genome-wide RNAi screen identifies genes involved in intestinal pathogenic bacterial infection Article de journal

Science, 325 (5938), p. 340–343, 2009, ISSN: 1095-9203.

Résumé | Liens | BibTeX | Étiquettes: *Genome, *RNA Interference, Animal, Animals, Cell Proliferation, Drosophila melanogaster/*genetics/immunology/*microbiology, Drosophila Proteins/genetics/metabolism, Epithelial Cells, Epithelial Cells/cytology/physiology, ferrandon, Genetically Modified, Genome, Hemocytes, Hemocytes/immunology/metabolism/microbiology, Homeostasis, Immunity, Innate, Innate/*genetics, Insect, Intestinal Mucosa, Intestinal Mucosa/cytology/immunology/metabolism/microbiology, Janus Kinases, Janus Kinases/genetics/metabolism, M3i, Models, RNA Interference, Serratia Infections, Serratia Infections/genetics/*immunology/microbiology, Serratia marcescens, Serratia marcescens/*immunology/physiology, Signal Transduction, STAT Transcription Factors, STAT Transcription Factors/genetics/metabolism, Stem Cells, Stem Cells/cytology/physiology

2008

Roetzer, Andreas; Gregori, Christa; Jennings, Ann Marie; Quintin, Jessica; Ferrandon, Dominique; Butler, Geraldine; Kuchler, Karl; Ammerer, Gustav; Schüller, Christoph

Candida glabrata environmental stress response involves Saccharomyces cerevisiae Msn2/4 orthologous transcription factors Article de journal

Mol. Microbiol., 69 (3), p. 603–620, 2008, ISSN: 1365-2958.

Résumé | Liens | BibTeX | Étiquettes: Animals, Candida glabrata, Candidiasis, DNA-Binding Proteins, ferrandon, Fungal, Fungal Proteins, Gene Expression Profiling, Gene Expression Regulation, Genetic, Humans, M3i, Oligonucleotide Array Sequence Analysis, Osmotic Pressure, Regulon, Saccharomyces cerevisiae Proteins, Transcription, Transcription Factors, Virulence, Yeasts

2007

Ferrandon, Dominique; Imler, Jean-Luc; Hetru, Charles; Hoffmann, Jules A

The Drosophila systemic immune response: sensing and signalling during bacterial and fungal infections Article de journal

Nat Rev Immunol, 7 , p. 862–74, 2007.

Résumé | BibTeX | Étiquettes: Animals, Bacterial Infections/*immunology/microbiology, Drosophila melanogaster/genetics/*immunology/microbiology, ferrandon, hoffmann, imler, Immunity, M3i, Mycoses/*immunology/microbiology, Natural/genetics, Signal Transduction/genetics/*immunology

Ferrandon, Dominique

Ubiquitin-proteasome: pallbearer carries the deceased to the grave Article de journal

Immunity, 27 (4), p. 541–544, 2007, ISSN: 1074-7613.

Résumé | Liens | BibTeX | Étiquettes: *Models, Animals, Apoptosis, Apoptosis/*physiology, ferrandon, Immunological, M3i, Macrophages, Macrophages/immunology/metabolism, Models, Phagocytosis, Phagocytosis/*physiology, Proteasome Endopeptidase Complex, Proteasome Endopeptidase Complex/*metabolism, ubiquitin, Ubiquitin/*metabolism

Ferrandon, Dominique; Gottar, Marie; Gobert, Vanessa

[New mechanism for detection of infections using the innate immune system of animals] Article de journal

Med Sci (Paris), 23 (8-9), p. 707–709, 2007, ISSN: 0767-0974.

Liens | BibTeX | Étiquettes: Animal, Animals, Drosophila/immunology, ferrandon, Gram-Positive Bacteria, Gram-Positive Bacteria/pathogenicity, Gram-Positive Bacterial Infections, Gram-Positive Bacterial Infections/immunology, Humans, Immune System, infection, Infection/*diagnosis/*immunology, M3i, Models

Nehme, Nadine T; Liégeois, Samuel; Kele, Beatrix; Giammarinaro, Philippe; Pradel, Elizabeth; Hoffmann, Jules A; Ewbank, Jonathan J; Ferrandon, Dominique

A model of bacterial intestinal infections in Drosophila melanogaster Article de journal

PLoS Pathog., 3 (11), p. e173, 2007, ISSN: 1553-7374.

Résumé | Liens | BibTeX | Étiquettes: Animal, Animals, Disease Models, Electron, ferrandon, fluorescence, Hemolymph, hoffmann, Host-Pathogen Interactions, Immunohistochemistry, Intestines, M3i, Microscopy, Reverse Transcriptase Polymerase Chain Reaction, Serratia Infections, Serratia marcescens, Transmission

2006

Gottar, Marie; Gobert, Vanessa; Matskevich, Alexey A; Reichhart, Jean-Marc; Wang, Chengshu; Butt, Tariq M; Belvin, Marcia; Hoffmann, Jules A; Ferrandon, Dominique

Dual detection of fungal infections in Drosophila via recognition of glucans and sensing of virulence factors Article de journal

Cell, 127 (7), p. 1425–1437, 2006, ISSN: 0092-8674.

Résumé | Liens | BibTeX | Étiquettes: Animals, Antibody Formation, Beauveria, Candida albicans, Carrier Proteins, Cellular, ferrandon, Glucans, hoffmann, Immunity, Immunological, M3i, Metarhizium, Models, Polysaccharides, reichhart, Serine Endopeptidases, Signal Transduction, Virulence Factors

2005

Kocks, Christine; Cho, Ju Hyun; Nehme, Nadine; Ulvila, Johanna; Pearson, Alan M; Meister, Marie; Strom, Charles; Conto, Stephanie L; Hetru, Charles; Stuart, Lynda M; Stehle, Thilo; Hoffmann, Jules A; Reichhart, Jean-Marc; Ferrandon, Dominique; Rämet, Mika; Ezekowitz, Alan R B

Eater, a transmembrane protein mediating phagocytosis of bacterial pathogens in Drosophila Article de journal

Cell, 123 (2), p. 335–346, 2005, ISSN: 0092-8674.

Résumé | Liens | BibTeX | Étiquettes: Amino Acid, Amino Acid Motifs, Animals, Bacterial Infections, Cell Surface, Embryo, Escherichia coli, ferrandon, Flow Cytometry, Frameshift Mutation, Genes, Histidine, hoffmann, In Situ Hybridization, Insect, Insect Proteins, M3i, Macrophages, Membrane Proteins, messenger, Nonmammalian, Open Reading Frames, Phagocytosis, Receptors, reichhart, RNA, RNA Interference, Sequence Homology, Serratia marcescens

2004

Ferrandon, Dominique; Royet, Julien

La réponse immunitaire chez la Drosophile Article de journal

Regards sur la biochimie, 1 , p. 27–33, 2004.

BibTeX | Étiquettes: ferrandon, M3i

Ferrandon, Dominique; Imler, Jean-Luc; Hoffmann, Jules A

Sensing infection in Drosophila: Toll and beyond Article de journal

Semin Immunol, 16 , p. 43–53, 2004, ISSN: 1044-5323.

Résumé | BibTeX | Étiquettes: Animals, Carrier Proteins/chemistry/immunology/physiology, Cell Surface/immunology/*physiology, Drosophila Proteins/chemistry/immunology/*physiology, Drosophila/genetics/*immunology/microbiology, ferrandon, Fungi/immunology, Gene Expression Regulation, Gram-Negative Bacterial Infections/immunology, Gram-Positive Bacterial Infections/immunology, hoffmann, imler, Immunological, Insect Proteins/chemistry/immunology/physiology, M3i, Models, Non-U.S. Gov't, Receptors, Signal Transduction/immunology/physiology, Support

Imler, Jean-Luc; Ferrandon, Dominique; Royet, Julien; Reichhart, Jean-Marc; Hetru, Charles; Hoffmann, Jules A

Toll-dependent and Toll-independent immune responses in Drosophila Article de journal

Journal of Endotoxin Research, 10 (4), p. 241–246, 2004, ISSN: 0968-0519.

Résumé | Liens | BibTeX | Étiquettes: Acute-Phase Proteins, Animals, Blood Proteins, Cell Surface, ferrandon, hoffmann, imler, Insect Proteins, M3i, Membrane Glycoproteins, Receptors, reichhart, Toll-Like Receptor 5, Toll-Like Receptors, Up-Regulation

2003

Gobert, Vanessa; Gottar, Marie; Matskevich, Alexey A; Rutschmann, Sophie; Royet, Julien; Belvin, Marcia; Hoffmann, Jules A; Ferrandon, Dominique

Dual activation of the Drosophila toll pathway by two pattern recognition receptors Article de journal

Science, 302 (5653), p. 2126–2130, 2003, ISSN: 1095-9203.

Résumé | Liens | BibTeX | Étiquettes: Animals, Carrier Proteins, Cell Surface, DNA Transposable Elements, ferrandon, Gene Expression, Genes, Gram-Negative Bacteria, Gram-Positive Bacteria, Hemolymph, hoffmann, Hypocreales, Insect, Insect Proteins, M3i, Mutation, Phenotype, Receptors, Serine Endopeptidases, Toll-Like Receptors

Kurz, Léopold C; Chauvet, Sophie; Andrès, Emmanuel; Aurouze, Marianne; Vallet, Isabelle; Michel, Gérard P F; Uh, Mitch; Celli, Jean; Filloux, Alain; Bentzmann, Sophie De; Steinmetz, Ivo; Hoffmann, Jules A; Finlay, Brett B; Gorvel, Jean-Pierre; Ferrandon, Dominique; Ewbank, Jonathan J

Virulence factors of the human opportunistic pathogen Serratia marcescens identified by in vivo screening Article de journal

Embo J, 22 , p. 1451–60, 2003, ISBN: 0261-4189.

Résumé | Liens | BibTeX | Étiquettes: *Virulence, Animal, Caenorhabditis elegans/*microbiology, ferrandon, hoffmann, M3i, Mutation, Non-U.S. Gov't, Serratia marcescens/genetics/*pathogenicity, Support

2002

Gottar, Marie; Gobert, Vanessa; Michel, Tatiana; Belvin, Marcia; Duyk, Geoffrey; Hoffmann, Jules A; Ferrandon, Dominique; Royet, Julien

The Drosophila immune response against Gram-negative bacteria is mediated by a peptidoglycan recognition protein Article de journal

Nature, 416 , p. 640–644, 2002, ISBN: 0028-0836.

Résumé | Liens | BibTeX | Étiquettes: Animal, Anti-Infective Agents/metabolism, Carrier Proteins/biosynthesis/genetics/*immunology, Drosophila melanogaster/genetics/*immunology/*microbiology, Drosophila Proteins/genetics/metabolism, Epistasis, Female, ferrandon, Genes, Genetic, Genetic Predisposition to Disease, Gram-Negative Bacteria/*immunology/physiology, hoffmann, Human, Insect/genetics, M3i, Messenger/genetics/metabolism, Mutation, Non-U.S. Gov't, P.H.S., Phenotype, RNA, Signal Transduction, Support, Survival Rate, Transgenes/genetics, U.S. Gov't

Ferrandon, Dominique; Royet, Julien

La drosophile : un modèle pour l'étude de la réponse immunitaire des invertébrés Article de journal

Regards sur la biochimie, 1 , p. 27–33, 2002.

BibTeX | Étiquettes: ferrandon, M3i

Royet, Julien; Meister, Marie; Ferrandon, Dominique

Humoral and cellular responses in textitDrosophila innate immunity incollection

Ezekowitz, R A B; Hoffmann, J A (Ed.): Innate Immunity, The Humana Press Inc., Totowa, 2002.

BibTeX | Étiquettes: ferrandon, M3i

Rutschmann, Sophie; Kilinc, A; Ferrandon, Dominique

The Toll pathway is required for resistance to Gram-positive bacterial infections in Drosophila. Article de journal

J Immunol, 168 , p. 1542–1546, 2002.

BibTeX | Étiquettes: ferrandon, M3i

2001

Georgel, Philippe; Naitza, S; Kappler, Christine; Ferrandon, Dominique; Zachary, Daniel; Swimmer, C; Kopczynski, C; Duyk, G; Reichhart, Jean-Marc; Hoffmann, Jules A

Drosophila immune deficiency (IMD) is a death domain protein that activates antibacterial defense and can promote apoptosis Article de journal

Dev. Cell, 1 (4), p. 503–514, 2001, ISSN: 1534-5807.

Résumé | BibTeX | Étiquettes: Animals, Anti-Infective Agents, Apoptosis, Bacterial Infections, Caspases, Chromosome Mapping, Cysteine Proteinase Inhibitors, DNA Damage, Female, ferrandon, Gene Expression, hoffmann, I-kappa B Kinase, Immunocompromised Host, In Situ Nick-End Labeling, Insect Proteins, M3i, Male, Mutation, Phenotype, Protein Structure, Protein-Serine-Threonine Kinases, reichhart, Tertiary

Jung, Alain C; Criqui, M C; Rutschmann, Sophie; Hoffmann, Jules A; Ferrandon, Dominique

A microfluorometer assay to measure the expression of beta-galactosidase and green fluorescent protein reporter genes in single Drosophila flies Article de journal

BioTechniques, 30 (3), p. 594–598, 600–601, 2001, ISSN: 0736-6205.

Résumé | BibTeX | Étiquettes: Animals, beta-Galactosidase, Cytophotometry, ferrandon, Genes, Green Fluorescent Proteins, hoffmann, Luminescent Proteins, M3i, Reporter

2000

Rutschmann, Sophie; Jung, Alain C; Zhou, R; Silverman, N; Hoffmann, Jules A; Ferrandon, Dominique

Role of Drosophila IKK gamma in a toll-independent antibacterial immune response Article de journal

Nat. Immunol., 1 (4), p. 342–347, 2000, ISSN: 1529-2908.

Résumé | Liens | BibTeX | Étiquettes: Animals, Antigens, Bacterial, Cell Surface, ferrandon, Gene Expression Regulation, hoffmann, I-kappa B Kinase, Immunity, Innate, Insect Proteins, M3i, Membrane Glycoproteins, Protein-Serine-Threonine Kinases, Receptors, Signal Transduction, Toll-Like Receptors, Transcription Factors

Rutschmann, Sophie; Jung, Alain C; Hetru, Charles; Reichhart, Jean-Marc; Hoffmann, Jules A; Ferrandon, Dominique

The Rel protein DIF mediates the antifungal but not the antibacterial host defense in Drosophila Article de journal

Immunity, 12 (5), p. 569–580, 2000, ISSN: 1074-7613.

Résumé | BibTeX | Étiquettes: Animals, Antigens, Bacterial, DNA-Binding Proteins, ferrandon, Fungal, hoffmann, Immunity, Innate, M3i, reichhart, Transcription Factors

Ferrandon, Dominique; Hetru, Charles; Reichhart, Jean-Marc; Hoffmann, Jules A

L'immunité innée : de la drosophile à l'homme Article de journal

Pour la Science, Dossier Hors Série Octobre , p. 8–12, 2000.

BibTeX | Étiquettes: ferrandon, hoffmann, M3i, reichhart

Tzou, P; Ohresser, S; Ferrandon, Dominique; Capovilla, Maria; Reichhart, Jean-Marc; Lemaitre, Bruno; Hoffmann, Jules A; Imler, Jean-Luc

Tissue-specific inducible expression of antimicrobial peptide genes in Drosophila surface epithelia Article de journal

Immunity, 13 , p. 737–48., 2000, ISSN: 1074-7613.

Résumé | BibTeX | Étiquettes: *Genes, Animal, Anti-Infective Agents/*immunology/metabolism, Drosophila/genetics/*immunology, ferrandon, Gene Expression Regulation/*immunology, Genes, Glycoside Hydrolases/immunology, hoffmann, Human, imler, Insect, Insect Proteins/genetics/immunology, M3i, Non-U.S. Gov't, Organ Specificity, P.H.S., reichhart, Reporter, Support, Transfection, U.S. Gov't

1998

Ferrandon, Dominique; Jung, Alain C; Criqui, M; Lemaitre, Bruno; Uttenweiler-Joseph, S; Michaut, Lydia; Reichhart, Jean-Marc; Hoffmann, Jules A

A drosomycin-GFP reporter transgene reveals a local immune response in Drosophila that is not dependent on the Toll pathway Article de journal

EMBO J., 17 (5), p. 1217–1227, 1998, ISSN: 0261-4189.

Résumé | Liens | BibTeX | Étiquettes: Animals, bacteria, Cell Surface, Developmental, Digestive System, Epithelium, Fat Body, Female, ferrandon, Fungal, Gene Expression Regulation, Genes, Green Fluorescent Proteins, hoffmann, Insect Proteins, Larva, Luminescent Proteins, M3i, Male, Membrane Glycoproteins, Organ Specificity, Receptors, reichhart, Reporter, Respiratory System, Spores, Toll-Like Receptors, Trachea, Transgenes

Reichhart, Jean-Marc; Ferrandon, Dominique

Green Balancers. Article de journal

D. I. S., 81 , p. 201–202, 1998.

Résumé | BibTeX | Étiquettes: ferrandon, M3i, reichhart

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